Early Breast Cancer

From Screening to Multidisciplinary Management, Third Edition

John R Benson, Gerald P.H. Gui, Todd Tuttle

• Publisher: CRC Press
• Year: 2013
• eBook ISBN:
  9781040163061
• Topic: Medicine
• Subtopic: Diagnostics Imaging

First Prize, BMA Medical Book Awards 2013Breast cancers are now detected earlier and are thus more likely to be confined to the breast itself and regional nodes. Many of these tumours will have minimal proclivity for hematogenous dissemination and formation of micrometastases. On the other hand, some patients have micrometastatic diseases which can

Table of contents

• Cover
• Half Title
• Title Page
• Copyright Page
• Contributors
• Preface
• Foreword by Dame Mary Archer
• SECTION 1: RISK ASSESSMENT AND PREVENTION OF BREAST CANCER
• 1. An introduction to screening for breast cancer
• 2. Mammographic density as an early indicator of breast cancer
• 3. Genetic predisposition and breast screening
• 4. Application of new genomic technologies to breast cancer risk assessment
• 5. Endocrine prevention of breast cancer
• SECTION 2: BREAST CANCER SCREENING
• 6. The biological basis for breast cancer screening and its relevance to treatment
• 7. Interval cancers
• 8. Survival advantage of screen-detected cancer over stage-matched symptomatic cancer
• 9. Mammography screening for women under age 50
• 10. Mammographic screening in women aged 50 years and above
• 11. The organization of breast screening
• 12. Quality assurance and evaluation of outcomes in the NHS breast screening programme
• SECTION 3: BREAST CANCER—DIAGNOSTIC EVALUATION
• 13. Clinical assessment of symptomatic patients
• 14. Film reading and recall from screening mammography
• 15. Radiology of the normal breast and differential diagnosis of benign breast lesions
• 16. Breast masses
• 17. Asymmetry and architectural distortion
• 18. The radial scar
• 19. Role of ultrasound in the diagnosis of breast cancer 169 Hannah Gay, Steven D. Allen
• 20. The role of MRi in preoperative evaluation and postoperative follow-up of breast cancer patients 180 Richard J. Bleicher
• 21. PET scanning and breast cancer management
• SECTION 4: TISSUE DIAGNOSIS
• 22. Core biopsy of breast lesions
• 23. Vacuum-assisted breast biopsy
• 24. Preoperative localization of impalpable breast lesions
• SECTION 5: BREAST PATHOLOGY
• 25. The normal breast and benign breast lesions
• 26. Histological risk factors, prognostic indicators, and staging
• 27. Premalignant and borderline lesions: ductal and lobular carcinoma in situ
• 28. invasive breast carcinoma
• 29. Molecular investigation of breast cancer
• SECTION 6: MULTIDISCIPLINARY MANAGEMENT OF BREAST CANCER
• 30. The role of multidisciplinary teams in breast cancer management
• Cath Taylor, Amanda Shewbridge,
• 31. Shared decision-making for breast cancer patients Catharine F. Clay, Alice O. Andrews,
• 32. The evolving role of the breast care nurse in the management of patients with early breast cancer 322 Rebecca Llewellyn-Bennett, Jane Barker,
• 33. Informed consent in the management and research of breast cancer
• SECTION 7: SURGICAL MANAGEMENT OF EARLY-STAGE BREAST CANCER
• 34. Ductal carcinoma in situ of the breast
• 35. Principles of surgical treatment of invasive breast cancer
• 36. The optimum resection margin in breast conservation surgery
• 37. Skin-sparing forms of mastectomy
• 38. Locoregional recurrence of breast cancer
• 39. Management of the axilla I
• 40. Management of the axilla II
• SECTION 8: TECHNIQUES FOR BREAST IRRADIATION
• 41. Radiation therapy following breast conserving surgery or mastectomy
• 42. Partial breast irradiation
• 43. Targeted intraoperative radiotherapy for breast cancer: not all cancers in the breast will grow 455 Jayant S. Vaidya, John R. Benson, Jeffrey S. Tobias
• SECTION 9: SYSTEMIC THERAPIES FOR EARLY-STAGE BREAST CANCER
• 44. Systemic hormonal therapies for early-stage breast cancer
• 45. Adjuvant chemotherapy and biological therapies for early-stage breast cancer
• 46. Primary systemic therapy in breast cancer
• SECTION 10: EARLY-STAGE BREAST CANCERSPECIAL CIRCUMSTANCES
• 47. Breast cancer in the elderly
• 48. Breast cancer and pregnancy
• 49. Male breast cancer
• 50. Trends in the use of contralateral prophylactic mastectomy
• 51. The principles of breast reconstructive surgery