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Narcolepsy and Hypersomnia
About this book
Ten years ago, D.M. Rowe introduced the bestselling CRC Handbook of Thermoelectrics to wide acclaim. Since then, increasing environmental concerns, desire for long-life electrical power sources, and continued progress in miniaturization of electronics has led to a substantial increase in research activity involving thermoelectrics. Reflecting the latest trends and developments, the Thermoelectrics Handbook: Macro to Nano is an extension of the earlier work and covers the entire range of thermoelectrics disciplines.Serving as a convenient reference as well as a thorough introduction to thermoelectrics, this book includes contributions from 99 leading authorities from around the world. Its coverage spans from general principles and theoretical concepts to material preparation and measurements; thermoelectric materials; thermoelements, modules, and devices; and thermoelectric systems and applications. Reflecting the enormous impact of nanotechnology on the field-as the thermoelectric properties of nanostructured materials far surpass the performance of conventional materials-each section progresses systematically from macro-scale to micro/nano-scale topics. In addition, the book contains an appendix listing major manufacturers and suppliers of thermoelectric modules.There is no longer any need to spend hours plodding through the journal literature for information. The Thermoelectrics Handbook: Macro to Nano offers a timely, comprehensive treatment of all areas of thermoelectrics in a single, unified reference.
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Information
Table of contents
- Cover Page
- Halftitle Page
- LUNG BIOLOGY IN HEALTH AND DISEASE
- Title Page
- Copyright Page
- Introduction
- Preface
- Contributors
- Contents
- 1 Historical Aspects of Narcolepsy
- 2 English Translations of the First Clinical Reports on Narcolepsy by Gelineau and on Cataplexy by Westphal in the Late 19th Century, with Commentary
- 3 Historical Aspects of the Treatment for Narcolepsy
- 4 Narcolepsy and Hypersomnia: Immunogenetic Aspects of Narcolepsy—Past, Present, and Future
- 5 The Hypocretins: Discovery and Emerging Role as Integrators of Physiological Signals
- 6 Cataplexy
- 7 Effect of Age on Narcolepsy
- 8 Narcolepsy in Children and Adolescents
- 9 Idiopathic Hypersomnia
- 10 Kleine-Levin Syndrome and Other Recurrent Hypersomnias
- 11 Spectrum of Narcolepsy
- 12 Sleep Paralysis, State Transition Disruptions, and Narcolepsy
- 13 Epidemiology of Narcolepsy: Development of the Ullanlinna Narcolepsy Scale
- 14 Epidemiology of Narcolepsy
- 15 Automatic Behavior, Sleep Paralysis, Hypnagogic Hallucinations, Cataplexy: Narcolepsy Spectrum and Alternate Etiologies
- 16 Neurophysiology of Cataplexy and Cataplexy-Like Phenomena
- 17 Abnormal Motor Activity During Sleep in Narcolepsy
- 18 Circadian and Ultradian Aspects in Narcolepsy
- 19 Homeostatic Sleep Regulation in Narcolepsy
- 20 Daytime Variations in Alertness/Drowsiness and Vigilance in Narcolepsy/Cataplexy
- 21 Molecular Characterization of Hypocretin/Orexin and Melanin Concentrating Hormone Neurons: Relevance to Narcolepsy
- 22 Nocturnal Polysomnography, Multiple Sleep Latency Test and Maintenance of Wakefulness Test in Narcolepsy
- 23 Canine Narcolepsy: History and Pathophysiology
- 24 Vigilance Tests in Narcolepsy
- 25 Lessons from Sleepy Mice: Narcolepsy-Cataplexy and the Orexin Neuropeptide System
- 26 Hypocretin-1 Studies in Cerebrospinal Fluid: European Experience
- 27 CSF Hypocretin-1/Orexin-A in Narcolepsy: Technical Aspects and Clinical Experience in the United States
- 28 Hypocretin Pathology in Human Narcolepsy
- 29 Symptomatic Narcolepsy with Cataplexy and Without Cataplexy or Hypersomnia, with and Without Hypocretin (Orexin) Deficiency
- 30 Poststroke and Posttraumatic Hypersomnia
- 31 Potential Mechanisms of the Wake-Promoting Action of Hypocretin/Orexin
- 32 Normal Role of Hypocretin/Orexin
- 33 Role of Hypocretin/Orexin in the Neurobiology of Sleep and Alertness
- 34 Hypocretin, GABAb Receptors and Sleep
- 35 The Activity Profile of Hypocretin Neurons in the Freely Moving Rat
- 36 Input and Output of Orexin/Hypocretin Neurons: Link Between Arousal Pathways and Feeding Behavior
- 37 Human Leukocyte Antigen and Narcolepsy: Present Status and Relationship with Familial History and Hypocretin Deficiency
- 38 Non-HLA Genes in Narcolepsy
- 39 Mutation Screening of the Hypocretin System Genes in Narcolepsy
- 40 Environmental Factors in Narcolepsy
- 41 Autoimmune Studies in Narcolepsy
- 42 Metabolic Abnormalities in Human Narcolepsy
- 43 Hormonal Abnormalities in Hypocretin/Orexin Deficient Human Narcolepsy
- 44 Psychosocial Impact of Narcolepsy
- 45 Narcolepsy and Driving
- 46 Comorbidity in Narcolepsy
- 47 The Behavioral Management of Narcolepsy
- 48 Pharmacology of CNS Stimulants
- 49 Anticataplectic Medications
- 50 Modafinil: Mechanisms of Action
- 51 Modafinil: The European Experience
- 52 Modafinil: The U.S. Experience
- 53 Molecular and Cellular Actions of g-Hydroxybutyric Acid: Possible Mechanisms Underlying GHB Efficacy in Narcolepsy
- 54 Sodium Oxybate for the Treatment of Narcolepsy
- 55 Perspectives for New Treatments: An Update
- 56 Diagnostic Criteria for Syndromes of Excessive Daytime Sleepiness
- Appendix A Guidelines for the Appropriate Use of CSF Measurements to Diagnose Narcolepsy
- Appendix B Treatment Guidelines
- Index