
Basics and Clinical Applications of Drug Disposition in Special Populations
- 483 pages
- English
- PDF
- Available on iOS & Android
Basics and Clinical Applications of Drug Disposition in Special Populations
About this book
An up-to-date exploration of techniques for effectively treating patients from special populations
In Basics and Clinical Applications of Drug Disposition in Special Populations, a team of distinguished researchers delivers a timely and authoritative discussion of how to predict drug disposition in special populations, including people with obesity, pediatric patients, geriatric patients, and patients with renal and hepatic impairment. The authors use pharmacokinetic models to account for variabilities between populations and to better predict drug disposition.
The book offers a collection of 15 chapters written by recognized experts in their respective fields. They cover topics ranging from the optimization of drug dosing regimens in specialized populations to model-based approaches in drug treatment among pediatrics.
Readers will also find:
- A thorough introduction to considerations and regulatory affairs for clinical research in special populations
- Comprehensive explorations of drug disposition in geriatrics, patients with hepatic insufficiency, and patients with renal insufficiency
- Practical discussions of model-based pharmacokinetic approaches
- Complete treatments of artificial intelligence in drug development
Perfect for practicing pharmacologists, pharmacists, and clinical chemists, Basics and Clinical Applications of Drug Disposition in Special Populations will also benefit medical professionals who provide medical and pharmaceutical care to special populations.
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Information
Table of contents
- Cover
- Title Page
- Copyright Page
- Dedication
- Contents
- About the Editors
- List of Contributors
- Foreword
- Preface
- Chapter 1 Pharmacokinetic Principles and Concepts: An Overview
- Chapter 2 Model-Based Pharmacokinetic Approaches
- Chapter 3 Physiologically Based Pharmacokinetic Modeling
- Chapter 4 Therapeutic Drug Monitoring in Special Populations
- Chapter 5 Optimization of Drug Dosing Regimen
- Chapter 6 Artificial Intelligence in Drug Development
- Chapter 7 Drug Disposition in Neonates and Infants
- Chapter 8 Drug Disposition in Adolescents
- Chapter 9 Drug Disposition in Pregnancy
- Chapter 10 Drug Disposition in Obesity
- Chapter 11 Drug Disposition in Critical Care Patients
- Chapter 12 Drug Disposition in Renal Insufficiency
- Chapter 13 Drug Disposition in Hepatic Insufficiency
- Chapter 14 Drug Disposition in Geriatrics
- Chapter 15 Considerations and Regulatory Affairs for Clinical Research in Special Populations
- Index
- EULA