Multivariate Statistical Machine Learning Methods for Genomic Prediction

Osval Antonio Montesinos López, Abelardo Montesinos López, José Crossa

• Publisher: Springer
• Year: 2022
• Print ISBN: 9783030890094
• eBook ISBN: 9783030890100
• Edition: 0
• Topic: Technology & Engineering
• Subtopic: Bioinformatics
• Index: Technology & Engineering

This book is open access under a CC BY 4.0 license

This open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool.  To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.

The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.

Table of contents

• Cover
• Front Matter
• 1. General Elements of Genomic Selection and Statistical Learning
• 2. Preprocessing Tools for Data Preparation
• 3. Elements for Building Supervised Statistical Machine Learning Models
• 4. Overfitting, Model Tuning, and Evaluation of Prediction Performance
• 5. Linear Mixed Models
• 6. Bayesian Genomic Linear Regression
• 7. Bayesian and Classical Prediction Models for Categorical and Count Data
• 8. Reproducing Kernel Hilbert Spaces Regression and Classification Methods
• 9. Support Vector Machines and Support Vector Regression
• 10. Fundamentals of Artificial Neural Networks and Deep Learning
• 11. Artificial Neural Networks and Deep Learning for Genomic Prediction of Continuous Outcomes
• 12. Artificial Neural Networks and Deep Learning for Genomic Prediction of Binary, Ordinal, and Mixed Outcomes
• 13. Convolutional Neural Networks
• 14. Functional Regression
• 15. Random Forest for Genomic Prediction
• Back Matter