Microbial Enzymes as Potential Biotherapeutics in Human Healthcare

Dileep Francis, Sabu Abdulhameed, Jayachandran K

• Publisher: CRC Press
• Year: 2025
• eBook ISBN: 9781040382639
• Topic: Biological Sciences
• Subtopic: Pharmacology
• Index: Biological Sciences

This book comprehensively reviews the diverse potential of microbial enzymes with therapeutic applications, covering their production, purification, and utilization. It examines their roles in combating various diseases, including inflammation, bacterial infections, cardiovascular conditions, and thrombotic disorders. The book highlights their pharmaceutical applications in drug formulation and bioactive compound production, with the aim of enhancing drug bioavailability, stability, and efficacy. Furthermore, the book explores the potential of microbial fibrinolytic enzymes to revolutionize treatments for thrombotic disorders. It also outlines the applications of microbial enzymes in targeting cancer cells, emphasizing their pivotal role in innovative treatment modalities. Additionally, the book presents the therapeutic applications of microbial lipases, from their use in lipid-lowering medications to the creation of lipase-based pharmaceuticals.

The chapters discuss the potential of microbial uricases in managing uric-acid-related disorders and the contribution of microbial enzymes in enhancing digestion and alleviating digestive disorders. Finally, the book delves into the vital role of regulatory authorities and intellectual property rights (IPR) in the commercialization of therapeutic microbial enzymes. As such, this book serves as a valuable resource for researchers, professionals, and students of microbiology, biotechnology, and pharmaceutical sciences.

Key Features:

• Reviews the therapeutic potential of microbial enzymes and their production and purification
• Examines the roles of microbial enzymes in combating a wide range of diseases, including inflammation, bacterial infections, cardiovascular conditions, and thrombotic disorders
• Highlights the pharmaceutical applications of microbial enzymes, focusing on drug formulation and the production of bioactive compounds to enhance drug bioavailability, stability, and efficacy
• Explores the therapeutic applications of microbial lipases, from lipid-lowering medications to the creation of lipase-based pharmaceuticals
• Presents the vital role of regulatory authorities and intellectual property rights (IPR) in the commercialization of therapeutic microbial enzymes

Table of contents

• Cover
• Half Title
• Title
• Copyright
• Contents
• Foreword
• Preface
• About the Editors
• Chapter 1 Exploring the Broad-Spectrum Potential of Microbial Therapeutic Enzymes
• Chapter 2 Therapeutic Applications of Microbial Enzymes: Recent Innovations and Future Prospects
• Chapter 3 Advances in the Production and Purification of Microbial Enzymes
• Chapter 4 Challenges in Stability, Delivery, and Targeting of Enzyme Therapeutics
• Chapter 5 Microbial Enzyme Therapeutics as Anti-Inflammatory Agents
• Chapter 6 Enzybiotics: An Emerging Frontier in Antibacterial Therapy
• Chapter 7 Microbial Fibrinolytic Enzymes and Their Therapeutic Potential
• Chapter 8 Microbial Enzymes in Cancer Therapy: Potential and Progress
• Chapter 9 Uricases from Microbes—Therapeutic Applications
• Chapter 10 Pharmaceutical Applications of Microbial Proteases
• Chapter 11 Tannase for the Production of Therapeutically Relevant Bioactive Compounds
• Chapter 12 Therapeutic Applications of Lipases
• Chapter 13 Microbial Collagenases: Unveiling Therapeutic Horizons and Diverse Applications
• Chapter 14 Harnessing Microbial Enzymes as Biosensors for Therapeutic Applications
• Chapter 15 Microbial Enzymes as Digestive Aids
• Chapter 16 Microbial Enzymes in Wound Healing and Tissue Regeneration
• Chapter 17 The Role of Regulatory Authorities and IPR in the Commercialization of Therapeutic Microbial Enzymes
• Index