Lupeol

Therapeutic Applications in Human Health and Disease

Hifzur R Siddique

• Publisher: CRC Press
• Year: 2025
• eBook ISBN: 9781040429372
• Topic: Medicine
• Subtopic: Microbiology

This book explores the therapeutic potential of Lupeol, a naturally occurring triterpenoid. The introductory chapters present its physicochemical properties, chemical modifications, and synthetic analogs, highlighting its potential against various diseases. The beneficial effects of Lupeol are explored across a broad range of health conditions, including its role in skin diseases and cardioprotective effects. The book highlights its antioxidant, anti-inflammatory, and chemopreventive effects, including its use in nanoparticle formulations for enhanced efficacy. Its protective properties for the kidneys, liver, and brain are also explored, along with its ability to sensitize resistant cells to chemotherapy and radiation. The chapters discuss the antimicrobial, antiparasitic, and anti-cancer effects of Lupeol, its role in inhibiting tumor growth, angiogenesis, and metastasis, and its modulation of transcription factors involved in disease pathways. Traditional uses of Lupeol-containing plants in systems like Unani medicine and its influence on gut microbiota and postbiotics for disease management are examined. Towards the end, the book also addresses Lupeol's safety, toxicology, and future clinical potential.

Key Features:

• Examines the therapeutic potential of Lupeol, a naturally occurring triterpenoid, through its diverse health applications
• Presents the physicochemical properties, chemical modifications, and synthetic analogs of Lupeol
• Highlights the antioxidant, anti-inflammatory, and chemopreventive effects of Lupeol and its role in nanoparticle formulations for enhanced efficacy in cancer treatments.
• Explores the cardioprotective, nephroprotective, hepatoprotective, and neuroprotective properties of Lupeol
• Addresses the safety, toxicology, and future clinical applications of Lupeol

It is a useful resource for researchers and students in pharmaceutical sciences, ethnopharmacology, and traditional medicine.

Table of contents

• Cover Page
• Half-Title Page
• Title Page
• Copyright Page
• Dedication Page
• Contents
• Preface
• Acknowledgments
• About the Editor
• Chapter 1 Chemical Alchemy of Lupeol: Synthesis, Derivatives Variability and Physiochemical Properties
• Chapter 2 The Cardioprotective Effect of Pentacyclic Triterpene Lupeol: Current Status and Future Prospects
• Chapter 3 Beneficial Effects of Lupeol Against Different Skin Diseases: Current Research and Future Direction
• Chapter 4 Antioxidant and Anti-Inflammatory Role of Triterpene Lupeol
• Chapter 5 Chemopreventive Effect of Lupeol and Lupeol Nanoparticles
• Chapter 6 Beneficial Hepatoprotective Effect of Triterpene Lupeol: Present Status and Future Perspectives
• Chapter 7 The Therapeutic and Protective Potential of Lupeol in Immune Modulation and Disease Prevention
• Chapter 8 The Beneficial Effect of Lupeol against Diabetes and Obesity
• Chapter 9 Chemosensitivity and Radiosensitivity of Triterpene Lupeol: Current Status and Future Perspective
• Chapter 10 Cell Growth Regulation and Molecular Targets of Lupeol
• Chapter 11 The Neuroprotective Effects of Lupeol
• Chapter 12 Lupeol as Antimicrobial Agent
• Chapter 13 Antitumor, Anti-Angiogenesis, Anti-Invasion, and Antimetastatic Effects of Lupeol
• Chapter 14 Roles of Lupeol-Rich Food on Gut Microbiota and Postbiotics in Human Diseases
• Chapter 15 Lupeol: A Natural Supplement for Enhanced Health
• Chapter 16 Safety and Toxicological Studies of Lupeol in Different Experimental Models
• Chapter 17 Importance of Lupeol Containing Plants and Plant Products in Traditional Medicine with an Emphasis on the Unani System of Medicine
• Chapter 18 Future Perspectives of Lupeol for Clinical Trials and Improvement of Activity
• Index