May We Make the World?
Gene Drives, Malaria, and the Future of Nature
- English
- ePUB (mobile friendly)
- Available on iOS & Android
About this book
May We Make the World? is an engaging reflection on the history, nature, goal, and meaning of using a new technological idea—CRISPR-based genetic engineering—to alter the genome of the mosquito that carries malaria. This technology, called a "gene drive," can alter the sex ratio in Anopheles gambiae mosquitoes, the key vector for falciparum, the deadliest form of malaria. P. Falciparum kills 400,000 people a year, largely the poorest children in the world among them. In her sobering examination of the issue, Laurie Zoloth considers the leading ethical arguments for and against gene drives, explores the regulatory efforts that have emerged long in advance of the science, and considers the philosophical questions raised by the struggle to eliminate malaria.
The development of a gene drive for malaria will have far-reaching implications for it represents the first use of genetic engineering in the natural world and the first creation of a genetic variant intended to spread in the African wild beyond human control. Drawing on two decades of work, Zoloth brilliantly argues that we can understand the complex moral issues at stake only by carefully reflecting on the science, the nature of the local and global discourse about genetic engineering, and the long history of malaria, which—as it transformed from a worldwide disease to a tropical one—reshaped the world as we know it.
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Information
Table of contents
- Cover
- Series Page
- Title Page
- Copyright
- Dedication
- Epigraph
- Contents
- Acknowledgments
- Introduction
- 1. The World as We Know It: Malaria and Its History
- 2. The World as It Is Imagined: Gene Drives for Malaria
- 3. The World as We Order It: A Review of Regulation
- 4. The World as We Speak It: Stakeholder Engagement and African Discourses
- 5. The World of Dissent: Listening to Opposition
- 6. The World as We Judge It: Ethical Issues Considered
- Conclusion: Making the Moral World
- Index
- Series List