Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject.

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Yes, you can access Fast Facts: Comprehensive Genomic Profiling by Bernardo L. Rapoport,Giancarlo Troncone,Fernando Schmitt,Simon Nayler,Bernardo L., Rapoport,Giancarlo, Troncone,Fernando, Schmitt,Simon, Nayler in PDF and/or ePUB format. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

eBook ISBN

Topic

Cover
Title Page
Copyright
Contents
Glossary and list of abbreviations
Introduction
1. Genetic mutations and biomarkers
2. Understanding next-generation sequencing
3. Elements of comprehensive genomic profiles
4. Role in precision oncology
5. Predictive and prognostic biomarkers
6. Overcoming barriers to genotype-directed therapy
Useful resources
Appendix: about the authors
Index

About this book

Frequently asked questions

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Table of contents