Functional Connectivity of the Human Brain

From Mechanisms to Clinical Applications

Maria Assunta Rocca, Massimo Filippi, Maria A. Rocca

• Publisher: Academic Press
• Year: 2025
• Topic: Biological Sciences
• eBook ISBN:
  9780443156793
• Subtopic: Science Research & Methodology
• Index: Biological Sciences

Functional Connectivity of the Human Brain: From Mechanisms to Clinical Applications is a comprehensive review of mechanisms and analysis of methods of functional connectivity to map brain organization in healthy individuals and sick patients. Providing full coverage of the discipline for a wide audience of different research and clinical specialists, this volume begins with descriptions of mechanisms of functional connectivity and methodological approaches to quantify it, followed by a focus on how functional connectivity has been used to describe brain function in healthy people and to characterize network disruption in diseased conditions. This practical balance in book structure is suitable for readers with a technical or clinical orientation, providing background that is easy to approach for clinicians or scientists. Chapters examine fMRI and electrophysiological techniques, brain maturation, aging, and cognitive neurosciences, as well as functional connectivity in neuroinflammatory, neurodegenerative, and neuropsychiatric conditions. Future perspectives look forward to functional connectivity in multimodal analysis, artificial intelligence, and more. This book will be of use to a wide audience working on functional connectivity experiments, as well as any courses on the topic. - Covers the main mechanisms of functional connectivity - Provides an overview of the main methodological aspects to map brain organization - Describes state-of-the-art achievements obtained with functional connectivity to study network functioning in healthy individuals and sick patients - Discusses future developments in the field

Table of contents

• Title of Book
• Chapter 1. Functional connectivity: Definition and signal origins
• Chapter 2. Assessing functional connectivity: the role of functional MRI and electrophysiological techniques
• Chapter 3. Analysis methods for functional connectivity: from seed-regions to data-driven approaches
• Chapter 4. Causal connections in the brain: from functional to causal connectivity
• Chapter 5. Exploring functional connectivity using graph theoretical analysis
• Chapter 6. Time-varying analysis of functional connectivity
• Chapter 7. Trajectories of functional connectivity in brain maturation
• Chapter 8. Trajectories of brain functional connectivity in brain aging
• Chapter 9. Application of functional connectivity to cognitive neurosciences
• Chapter 10. Functional connectivity in neuroinflammatory conditions
• Chapter 11. Functional connectivity in neurodegenerative conditions
• Chapter 12. Functional connectivity in neuropsychiatric diseases
• Chapter 13. Current limitations in functional connectivity assessment: suggestions for analysis improvements
• Chapter 14. Future perspectives of functional connectivity: Advances in data acquisition and analysis
• Index