Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers

Rajendra Awasthi, Santosh Kumar Singh, Anurag Kumar Singh

• Publisher: Elsevier
• Year: 2025
• Topic: Technology & Engineering
• eBook ISBN:
  9780443248030
• Subtopic: Biotechnology in Medicine
• Index: Technology & Engineering

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous silicon nanomaterials, with a special emphasis on drug delivery. This book introduces the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, such as vaccine development, drug delivery, and tissue engineering. It also contains new insights on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, cancer immunotherapy, and more. Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers is of interest to researchers in the fields of materials science, nanotechnology, pharmaceutical science, biomedical engineering, and cancer research. - Details synthesis approaches and methodologies for porous silicon-based nanocarriers, enabling structural understanding and therapeutic applications - Highlights the role of silica nanoparticles in targeted drug delivery, emphasizing their impact on cancer therapy, immunotherapy, neurodegenerative disorders, and other biomedical applications - Explores clinical aspects and trials of silica nanoparticles for treatment options

Table of contents

• Cover image
• Title page
• Copyright
• Table of Contents
• Contributors
• CHAPTER 1 Historical advancements in targeted nanoscale drug delivery systems
• CHAPTER 2 Synthesis of porous silicon–based nanoparticles
• CHAPTER 3 Characterization techniques for mesoporous silicon nanoparticles
• CHAPTER 4 Mesoporous silicon for solubility enhancement of drugs
• CHAPTER 5 Porous silicon–based nanocarriers for tumor targeting
• CHAPTER 6 Porous silica and related composites for topical drug delivery
• CHAPTER 7 Porous silicon nanocarriers for the management of neurodegenerative disorders
• CHAPTER 8 Functionalized silica nanocarriers for brain-targeted delivery
• CHAPTER 9 Porous silicon-based materials in nanoneedle and microneedle-based drug delivery systems
• CHAPTER 10 Porous silicon-based drug delivery carriers in cancer management
• CHAPTER 11 Stimuli-responsive silica nanoparticles: Smart systems for controlled drug delivery
• CHAPTER 12 Mesoporous silica-based nanocarriers in pulmonary drug delivery
• CHAPTER 13 Porous silicon nanoparticles in codelivery of drugs for improved cellular uptake and targeted drug delivery
• CHAPTER 14 Recent advances in porous silicon–based technology for biomedical applications
• CHAPTER 15 Immunotherapeutic applications of porous silicon nanoparticles
• CHAPTER 16 Bioengineered porous silicon nanoparticles in vaccine development
• CHAPTER 17 Bioavailability enhancement of poorly soluble drugs with mesoporous silicon
• CHAPTER 18 Silica nanoparticles in clinical trials
• CHAPTER 19 Mesoporous silica nanoparticles for therapeutic uses: From bench to clinics
• CHAPTER 20 Future perspectives of mesoporous silica-based nanocarriers in drug delivery
• Index