NanoPDT

Nanomaterials-Enhanced Photodynamic Therapy

Saeid Moghassemi, Ricardo Bentes Azevedo, Christiani Andrade Amorim

• Publisher: Academic Press
• Year: 2025
• eBook ISBN:
  9780443404320
• Topic: Medicine
• Subtopic: Pharmaceutical, Biotechnology & Healthcare Industry

NanoPDT: Nanomaterials-Enhanced Photodynamic Therapy covers extensively the therapeutic potential of multifunctional nanosystems that has made so much progress within the biomedical and pharmaceutical research communities over recent decades. Traditional photodynamic therapy (PDT), however, faces several limitations, primarily due to the hydrophobic nature of photosensitizers (PS), which tend to aggregate in aqueous environments, resulting in inadequate biodistribution and limited bioavailability. These constraints significantly reduce the efficacy of photodynamic therapy. The book also explores the most relevant combination therapies available. Four chapters are dedicated to the combination of NanoPDT with other approaches like Immunotherapy, Radiotherapy, chemotherapy, and photothermal therapy. NanoPDT: Nanomaterials-Enhanced Photodynamic Therapy is an essential resource for pharmaceutical researchers, clinicians, and students in the fields of nanomedicine, oncology, and photodynamic therapy. It offers a thorough exploration of the latest advancements and future directions, providing valuable insights for those looking to enhance the efficacy and specificity of PDT through nanotechnology and its combined applications. The book's comprehensive coverage of both oncological and non-oncological applications makes it a crucial addition to the literature, bridging the gap between fundamental research and clinical practice. - Highlights clinical trials and case studies demonstrating the effectiveness of NanoPDT - Delivers in-depth insights into the principles, mechanisms, and advancements in photodynamic therapy - Provides comprehensive coverage of both oncological and non-oncological applications of NanoPDT - Explores innovative third-generation photosensitizers that combine nanomedicine with PDT to enhance treatment efficacy - Provides an extensive overview of NanoPDT combination therapies, including chemotherapy, radiotherapy, immunotherapy, and photothermal therapy

Table of contents

• Title of Book
• Chapter 1 Introduction to photodynamic therapy
• Chapter 2 Nanomaterials in photodynamic therapy
• Chapter 3 Nanophotodynamic therapy systems classification
• Chapter 4 Metal-based nanomaterials in photodynamic therapy
• Chapter 5 Quantum dots in photodynamic therapy
• Chapter 6 Carbon-based nanomaterials in photodynamic therapy
• Chapter 7 Polymer-based nanomaterials in photodynamic therapy
• Chapter 8 Lipid-based nanomaterials for enhanced photodynamic therapy
• Chapter 9 Next-generation nano-photodynamic and chemotherapy combinations: advances, mechanisms, and clinical prospects
• Chapter 10 Synergistic nano-photodynamic therapy/nano-photothermal therapy combination
• Chapter 11 Synergistic nanoparticle-enhanced photodynamic therapy and radiotherapy combination
• Chapter 12 Nanophotodynamic therapy and immunotherapy combination
• Chapter 13 Future trends of nanophotosensitizers and their regulatory
• Index