Myasthenia Gravis

Disease, Diagnosis and Management

Bhupendra G. Prajapati, Devesh U. Kapoor, Jaimin R. Shah

• Publisher: Academic Press
• Year: 2025
• eBook ISBN:
  9780443366482
• Topic: Medizin
• Subtopic: Krankheiten & Allergien

Myasthenia Gravis: Disease, Diagnosis and Management is a comprehensive resource that explores recent advancements in diagnosing and treating Myasthenia Gravis, a rare autoimmune disease affecting the neuromuscular junction. With contributions from global experts, this book addresses the increasing prevalence of Myasthenia Gravis, reflecting the latest in diagnostic techniques and novel therapies such as complement inhibitors and FcRn antagonists. It aims to support healthcare professionals in delivering optimal care through evidence-based insights and patient-centered approaches. The book is divided into several chapters, beginning with an overview of the pathogenesis and immunoregulatory defects in Myasthenia Gravis. Subsequent chapters cover diagnostic methods, non-immunosuppressive treatments, and biological therapies targeting the immune system. Key topics include the role of intravenous immunoglobulin (IVIg) and plasma exchange (PLEX) in severe exacerbations, thymectomy, molecular mechanisms, and the potential of hematopoietic stem cell transplants. The book also delves into precision medicine, AI applications, clinical trial considerations, and novel therapeutics like anti-FcRn antibodies. Management strategies for ocular Myasthenia Gravis, and a holistic view of living with the disease are also discussed. Myasthenia Gravis: Disease, Diagnosis and Management is invaluable for healthcare providers, physicians, immunologists, ophthalmologists, rheumatologists, physical therapists, pharmacists, and translators. It offers a modern guide to understanding and managing Myasthenia Gravis, integrating clinical expertise with the latest research to improve patient outcomes. - Explores pathogenesis, diagnosis, and treatment options for Myasthenia Gravis, providing a complete understanding of the disease - Highlights cutting-edge therapies like complement inhibitors and FcRn antagonists for improved patient outcomes - Ensures authoritative and up-to-date information contributed by global experts - Offers evidence-based strategies for healthcare professionals to optimize Myasthenia Gravis management - Integrates clinical expertise with patient-centered care for a well-rounded perspective on disease management

Table of contents

• Title of Book
• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• Dedication
• Dedication
• List of contributors
• About the editors
• Preface
• Acknowledgments
• Chapter 1 Introduction to myasthenia gravis and ocular myasthenia gravis
• Chapter 2 Diagnosis of myasthenia gravis
• Chapter 3 Nonimmunosuppressive treatment of myasthenia gravis
• Chapter 4 Therapeutic mechanisms and clinical impact of monoclonal antibodies in myasthenia gravis treatment
• Chapter 5 Novel immunotherapies for myasthenia gravis
• Chapter 6 Management of myasthenia gravis in severe exacerbation
• Chapter 7 Role of thymectomy in myasthenia gravis
• Chapter 8 Molecular Mechanisms of Myasthenia Gravis
• Chapter 9 Management of myasthenia gravis with hematopoietic stem cell transplant
• Chapter 10 Precision medicine in myasthenia gravis
• Chapter 11 Application of artificial intelligence in management of myasthenia gravis
• Chapter 12 Clinical trials and case studies considerations in myasthenia gravis
• Chapter 13 Antineonatal Fc receptor antibodies-based novel therapeutics
• Chapter 14 Management of ocular myasthenia gravis
• Chapter 15 Living with myasthenia gravis and future perspective
• Index