Insights into Migraine Treatments

Towards Personalized Medicine

Massimo Filippi, Roberta Messina

• Publisher: Academic Press
• Year: 2025
• eBook ISBN:
  9780443236501
• Topic: Scienze biologiche
• Subtopic: Biologia

Insights into Migraine Treatments offers a comprehensive overview to guide the selection of the most appropriate therapy for each patient within the landscape of migraine care. It explores the full spectrum of available treatments and their mechanisms of action, while addressing the challenges of individualized therapeutic decision-making. By presenting essential data on efficacy, safety, and biomarkers of treatment response, this book serves as a practical resource for tailoring interventions to patient-specific needs. With its solution-oriented approach, it is a valuable reference for clinicians and researchers striving to advance migraine management.Covering topics from the clinical characteristics of migraine to acute therapies, pharmacological and nonpharmacological preventive strategies, and clinical, neuroimaging, and neurophysiological biomarkers, this book is designed to meet the complex and evolving needs of migraine patients. - Provides up-to-date evidence on the efficacy and safety of acute and preventive migraine treatments - Enhances understanding of mechanisms of action and therapeutic targets across treatment options - Discusses emerging biomarkers that may predict individual treatment response, improving patient outcomes

Table of contents

• Title of Book
• Chapter 1 Clinical manifestations of migraine
• Chapter 2 Why, when, and how to treat migraine patients?
• Chapter 3 Acute treatments: nonsteroidal anti-inflammatory drugs, ergot alkaloids, triptans, and ditans
• Chapter 4 Acute treatments: neuromodulation and peripheral nerve blocks
• Chapter 5 Oral preventive treatments: antidepressants, antihypertensives, anticonvulsants, betablockers, and calcium channel blockers
• Chapter 6 Preventive treatments: onabotulinumtoxinA and peripheral nerve blocks
• Chapter 7 Nonpharmacological approaches in migraine prevention: neuromodulation, nutraceuticals, and behavioral approaches
• Chapter 8 Why target the calcitonin gene-related peptide pathway: Receptors, intracellular pathways, and its role in migraine pathophysiology
• Chapter 9 Gepants
• Chapter 10 Anti-CGRP monoclonal antibodies
• Chapter 11 Biomarkers of treatment response
• Chapter 12 Migraine treatments: what have we learned from neuroimaging?
• Chapter 13 Migraine treatments: what have we learned from neurophysiology?
• Chapter 14 Treatments to use in special circumstances: children, pregnancy, elderly
• Chapter 15 Unmet needs and future perspectives
• Index