Practical Heterocyclic Chemistry

A Lab Manual for Syntheses of Heterocycles

Vaidhyanathan Balasubramaniyan

• Publisher: Elsevier
• Year: 2025
• eBook ISBN:
  9780443328091
• Topic: Physical Sciences
• Subtopic: Organic Chemistry

Practical Heterocyclic Chemistry: A Lab Manual for Syntheses of Heterocycles delves into the entwined history of heterocyclic chemistry and general organic chemistry, tracing their evolution from crude isolation and utilization of bioactive natural products to their current, pivotal role in enhancing the quality of life for humanity and all living organisms. The book provides a concise overview of the enabling technologies and modern toolkits that facilitate complex general organic and heterocyclic syntheses, while also emphasizing the importance of safe and sustainable synthesis processes that are shaped by the game-changing principles of green chemistry.Readers are also made aware of crucial safety considerations in laboratory practice, including hazard mitigation related to starting materials, products, solvents, catalysts, and lab equipment handling. The book covers the essential laboratory skills needed for experiment design, execution, isolation, purification, and characterization, serving as a valuable resource for modern heterocyclic synthesis in academia and industry. - Over 110 exercises, with schemes containing full details to make selections easy, with step-by-step procedures and critical questions for a fair number among them• Exposure to applications of modern synthetic toolkits, Green Chemistry and various traditional, yet still popular, protocols of synthesis• Exercises include all major ring sizes and ring atoms• A simple notation to refer to the core structure of heterocycles presented in the manual

Table of contents

• Title of Book
• Cover image
• Title page
• Table of Contents
• Copyright
• Dedication
• About the author
• Preface
• Acknowledgments
• Why I write this manual?
• About the manual
• Index for the target molecules of the experiments in the manual
• Abbreviations for the references cited in the manual
• Chapter 1 Introduction
• Chapter 2 In the lab
• Chapter 3 List of experiments
• Chapter 4 Experiments
• Appendix A:
• Appendix B:. Physical constants for organic liquids
• Appendix C:. Physical constants for organic solids
• Appendix D: Physical constants for solvents
• Appendix E. List of inorganic substances used in experiments in this manual
• Appendix F: Pressure-temperature nomograph
• Index