Critical Analysis of Monoclonal Antibody Therapy in Transplantation
eBook - ePub

Critical Analysis of Monoclonal Antibody Therapy in Transplantation

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

Critical Analysis of Monoclonal Antibody Therapy in Transplantation

About this book

Critical Analysis of Monoclonal Antibody Therapy in Transplantation provides a critical analysis of monoclonal antibody therapies in transplantation. The book presents diverse approaches to monoclonal antibody therapy in transplantation and addresses some of the serious obstacles that remain both in understanding these mechanisms and in successfully applying them in clinical situations. The background and rationale for OKT3 therapy are examined and an extensive clinical experience with OKT3 induction therapy in cardiac transplantation is reviewed. The book also examines the background and rationale for the use of anti-TcR (??), anti-IL-2R, and anti-LFA-1 monoclonal antibodies in clinical transplantations. Other topics include the use of monclonal antibodies to CD4 and CD8 for the induction of adult transplantation tolerance in rodents and the possibilities for applying anti-idiotypical strategies that have proven useful in autoimmunity models to transplant recipients. Researchers and basic scientists involved in this field will find the book a fascinating and useful resource for their investigations.

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Information

Publisher
CRC Press
Year
2026
eBook ISBN
9781040896655
Topic
Medicine
Subtopic
Immunology

Table of contents

  1. Cover
  2. Title Page
  3. Copyright Page
  4. Preface
  5. Foreward
  6. The Editor
  7. Acknowledgments
  8. Contributors
  9. Table of Contents
  10. Chapter 1 Anti-CD3-Mediated Immunotherapy: A Murine Model
  11. Chapter 2 OKT3 in Allogenic Transplantation: Clinical Efficacy, Mode of Action, and Side Effects
  12. Chapter 3 The Use of OKT3 for Induction Therapy in Cardiac Transplantation
  13. Chapter 4 Anti-IL-2 Receptor and Anti-LFA-1 Monoclonal Antibodies in Transplantation: Rational and Nantes Clinical Experience
  14. Chapter 5 Transplantation Tolerance with Monoclonal Antibodies
  15. Chapter 6 Anti-CD4-Mediated Transplantation Tolerance: Mechanism and Memory
  16. Chapter 7 Prospects for Anti-Idiotype Therapy in Transplantation
  17. Index

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Yes, you can access Critical Analysis of Monoclonal Antibody Therapy in Transplantation by William J. Burlingham in PDF and/or ePUB format, as well as other popular books in Medicine & Immunology. We have over 1.5 million books available in our catalogue for you to explore.