Cushing Syndrome

History, Diagnosis and Treatment

Constantine A. Stratakis

• Publisher: Elsevier
• Year: 2026
• eBook ISBN:
  9780323993708
• Topic: Medicine
• Subtopic: Endocrinology & Metabolism

Cushing Syndrome: History, Diagnosis, and Treatment is written by top experts on the latest in genetics, molecular advances, and the diagnosis and treatment of Cushing syndrome. The book takes a historical approach to discuss the tremendous and unprecedented research development for this rare condition and includes information on recently approved treatments. It attempts to provide information on most issues surrounding Cushing syndrome and how to deal with its complications, the widening understanding of functional hypercortisolemia and other causes of endogenous cortisol production and its old and new treatment modalities, from pituitary to adrenal tumors, ectopic ACTH production, subclinical, cyclical Cushing syndrome, to aging and metabolic syndrome.The book has a section dedicated to our patients with the patients' experiences, which will add to the outcome research presented by the physicians. This is a must have reference for scientists and researchers with the latest information in diagnosing and treating this difficult-to-diagnose and difficult-to-treat condition and gives the clinician, a patient-centric approach to communicate with this particular group of patients. - Provides comprehensive "how to" information for diagnosis and treatment - Includes the latest information on genetics, all molecular advances, and new medical therapies - Presents a patient-centric approach with an emphasis on patients' perspectives and long-term effects of cortisol excess, well-being, and mental health

Table of contents

• Title of Book
• Chapter 1. Identification of Cushing's syndrome (CS) and its history from Harvey Cushing to today
• Chapter 2. Endogenous Cushing's syndrome: Causes and genetics
• Chapter 3. Animal models of CS: What do they teach us?
• Chapter 4. Exogenous (iatrogenic) Cushing syndrome: Most frequent uses of glucocorticoids and outcomes, including recommendations for recovery (postchemotherapy, asthma treatments, chronic use on rheumatoid, and/or skeletal disorders)
• Chapter 5. Factitious Cushing syndrome and factitious Cushing syndrome-by-proxy: Cases, diagnosis, and outcomes
• Chapter 6. Nonneoplastic hypercortisolism (pseudo-CS): Causes and long-term issues
• Chapter 7. Cushing’s disease: Pituitary tumors causing CS—Diagnosis and treatment
• Chapter 8. Adrenal tumors causing Cushing syndrome: Genetics, molecular advances, diagnosis, and treatment
• Chapter 9. Ectopic ACTH- or CRH-producing tumors and Cushing’s syndrome
• Chapter 10. Cushing syndrome in pediatrics: From molecular pathogenesis to therapeutic management
• Chapter 11. All about dexamethasone testing in Cushing's syndrome
• Chapter 12. CRH test: To do or not to do
• Chapter 13. Surgical management of CD: Techniques, complications, and recovery
• Chapter 14. Surgical issues for a patient with Cushing's syndrome: Techniques, complications, and recovery
• Chapter 15. Medical therapies for Cushing’s syndrome
• Chapter 16. CS and long-term effects on health, cognition, and function
• Chapter 17. Cushing syndrome in pregnancy
• Chapter 18. The patient with Cushing's syndrome: Perspectives, experiences, advice, and resources for physicians and other caregivers
• Index