Comprehensive Chemistry and Biology of Coumarins Scaffold

Shehryar Hameed, Khalid Mohammed Khan, Mehwish Solangi

• Publisher: Elsevier
• Year: 2026
• Topic: Biological Sciences
• eBook ISBN:
  9780443156519
• Subtopic: Biotechnology
• Index: Biological Sciences

Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules. - Provides a resource that is organized consistently based on targets and mechanisms of action from a molecular point-of-view - Emphasizes synthetic methodologies and their various medicinal applications - Critically analyzes and updates much of the widely dispersed content in one place

Table of contents

• Title of Book
• 1 General introduction of coumarin
• 2 Synthesis and reactivity
• 3 Naturally occurring coumarins in the development of commercial drugs
• 4 Multitargeted scaffold in medicinal chemistry: Potential anticancer agents
• 5 Role of coumarins in different infectious diseases
• 6 In the design and development of neurotherapeutics agents
• 7 Development as antiinflammatory and anticoagulant agents
• 8 Potential in antidiabetic and antioxidant therapies
• 9 Coumarin-based metal complexes and polymers
• 10 Recent advances in applications of coumarins: A brief discussion on patents and activities, status, and perspectives
• Glossary of terms
• Index