Mass Spectrometry

Applications and Recent Advances

Nahide Gülşah Deniz

• Publisher: IntechOpen
• Year: 2026
• eBook ISBN:
  9781836342007
• Print ISBN:
  9781836342014
• Topic: Physical Sciences

Mass spectrometry is an analytical technique used to characterize chemical compounds and biological molecules. Mass spectrometry has become one of the most powerful analytical technologies of the modern era, enabling precise molecular identification, structural characterization, and quantitative analysis across an expanding range of scientific disciplines. As instrumentation and computational methods continue to advance at an unprecedented pace, new possibilities are emerging for deeper molecular insight, more rapid workflows, and increasingly complex analytical challenges. Mass spectrometry is applicable across diverse fields, including forensic toxicology, metabolomics, proteomics, pharmaceutical and biopharmaceutical research, and clinical research. Mass spectrometers extend analytical capabilities across a range of clinical applications when coupled with gas or liquid chromatography. Mass spectrometry has evolved into a versatile tool across chemistry, biology, and the pharmaceutical sciences. Specific applications of mass spectrometry include drug testing and discovery, food contamination detection, pesticide residue analysis, isotope ratio determination, protein identification, and carbon dating. Sample preparation is crucial for successful mass spectrometry, particularly when analyzing complex matrices commonly encountered in clinical chemistry.  The primary purpose of this book is to open the possibilities and uses of mass spectrometry to a broader audience. This book provides a comprehensive overview of state-of-the-art applications of mass spectrometry for the characterization of organic compounds, materials, and biomaterials. In fact, this collective work will benefit students, teachers, and researchers across many areas interested in expanding their knowledge of mass spectrometry applied to organic chemistry, inorganic chemistry, analytical chemistry, nanotechnology, biotechnology, environmental science, materials science, and pharmaceutical sciences. Whether you are new to mass spectrometry or seeking a deep exploration of its latest advancements, this volume delivers a clear, insightful, and forward-looking perspective on one of analytical science's most dynamic fields.

Table of contents

• Mass Spectrometry - Applications and Recent Advances
• Contents
• Preface
• Chapter 1 - Advances in the Analysis of Contaminants, Illicit Drugs, Pharmaceuticals, and Hormones for Wastewater-Based Epidemiology (WBE) Using Automated Extraction and Detection by LC and GC-MS/MS: Evaluation of Method Eco-Friendliness and Practicality
• Chapter 2 - High-Throughput Glycomics Analysis Enabled by Multiplex Chemical Derivatization and Mass Spectrometry
• Chapter 3 - Ionization Techniques for Mass Spectral Analysis
• Chapter 4 - Mass Spectrometry Applications in Forensic Sciences
• Chapter 5 - Mass Spectrometry for In-Depth Study and Discovery of Marine Bioactive Metabolites