Laboratory Animal Medicine

James G. Fox, F. Claire Hankenson, Kelly A. Metcalf Pate, Kathleen R. Pritchett-Corning, Mark A. Suckow

• Publisher: Academic Press
• Year: 2026
• Edition: 4
• eBook ISBN:
  9780443137228
• Topic: Medicine
• Subtopic: Surgery & Surgical Medicine

**Selected for 2026 Doody's Core Titles in Veterinary Medicine**Laboratory Animal Medicine, Fourth Edition—a volume in the American College of Laboratory Animal Medicine (ACLAM) blue book series—is the authoritative reference on the biology, health, and care for species involved in research. Edited by recognized veterinary, operational, and research experts and endorsed as the official material for veterinary specialty certification by ACLAM, this work defines the standard for all aspects of humane laboratory animal care and science with animal models.This new edition contains significant changes in content and organization to reflect the evolution of the field. The animal welfare chapter has been moved to the beginning of the book to highlight this subject's importance. Other chapters have either been consolidated to encourage the reader to recognize commonalities such as those between guinea pigs, gerbils and hamsters, or separated out in recognition of expansions in knowledge and cross-species complexity as illustrated by separate new and old world primate chapters. Advances in practice, technology, and knowledge are highlighted in the chapters on genetically modified organisms, with updates on new techniques in genetic engineering and consideration of non-rodent genetically modified models; microbiological monitoring, with an increased emphasis on environmental monitoring and sentinel free colony health monitoring methods; regulatory compliance, with a comprehensive chapter on birds; employee health and safety, with expanded consideration of compassion fatigue; and animal models in biomedical research, with increased emphasis on experimental design and rigor. New chapters on animal models for microbiome, infectious disease, and transplant research have been added to serve as a reference for the community.This book is an excellent reference for veterinarians and research scientists, as well as program directors and facility managers employed in a variety of academic and corporate settings. This edition continues the tradition of this text in setting standards for the research animal science community as well as expanding and updating relevant and essential topics for this specialty field. - Covers the most important species used in life sciences research focusing on biology, diseases, and management - Provides a renewed focus on animal welfare and expanded coverage of non-human primates, fishes, avian models - Includes guidance on laboratory animal program and human resources management - Presents regulations, policies, and laws for laboratory animal management worldwide

Table of contents

• Title of Book
• Chapter 1. Laboratory Animal Medicine: Historical Perspectives
• Chapter 2. Research Animal Welfare
• Chapter 3. Laws, Regulations, and Policies Affecting the Use of Laboratory Animals
• Chapter 4. Principles of Genetic Modification in Laboratory Animal Species
• Chapter 5. Biology and Diseases of Mice
• Chapter 6. Biology and Diseases of Rats
• Chapter 7. Biology and Diseases of Guinea Pigs, Gerbils, and Hamsters
• Chapter 8. Biology and Diseases of Other Rodents
• Chapter 9. Biology and Diseases of Rabbits
• Chapter 10. Microbiological Quality Control for Laboratory Rodents
• Chapter 11. Biology and Diseases of Dogs
• Chapter 12. Biology and Diseases of Cats
• Chapter 13. Biology and Diseases of Ferrets
• Chapter 14. Biology and Diseases of Ruminants (Sheep, Goats, and Cattle)
• Chapter 15. Biology and Diseases of Swine
• Chapter 16. New World Nonhuman Primates
• Chapter 17. Old World Nonhuman Primates
• Chapter 18. Biology, Management, and Diseases of the Zebrafish
• Chapter 19. Biology and Diseases of Amphibians
• Chapter 20. Biology and Diseases of Reptiles
• Chapter 21. Birds in Biomedical Research
• Chapter 22. Animal Models in Biomedical Research
• Chapter 23. Techniques of Experimentation
• Chapter 24. Anesthesia, Analgesia, and Euthanasia
• Chapter 25. Factors that May Influence Animal Research
• Chapter 26. Design and Management of Animal Research Facilities
• Chapter 27. Comprehensive Occupational Health and Safety: Promoting Physical and Mental Well Being for Workers, Visitors, and Others Exposed to Research Animals and Their Tissues
• Chapter 28. Selected Zoonoses
• Chapter 29. Gnotobiotics
• Chapter 30. The Microbiome of Laboratory Animals
• Chapter 31. Infectious Disease Research and Biocontainment
• Chapter 32. Transplant Medicine (Including Allogeneic and Xenogeneic)
• Chapter 33. Program Management
• Chapter 34. Research Animal Behavior
• Index