Type 2 Diabetes Mellitus

Exploring Immunogenetic Pathways

Haamid Bashir, Shafat Ali, Yahya Fahad Mohammed Jamous

• Publisher: Elsevier
• Year: 2026
• eBook ISBN:
  9780443335914
• Topic: Medicine
• Subtopic: Endocrinology & Metabolism

Type 2 Diabetes Mellitus: Exploring Immunogenetic Pathways is a novel reference to gain a deep understanding of the genetic underpinnings and immune system dynamics in Type 2 Diabetes Mellitus (T2DM). It addresses a fundamental gap in the current literature by synthesizing complex information into accessible chapters serving as a roadmap for those needing to navigate the intricate landscape of immunogenetics. It equips readers with the tools to comprehend the underlying mechanisms, discover potential therapeutic strategies, and contribute to the ongoing dialogue in this rapidly advancing field. Real-world case studies and clinical scenarios are throughout the book to illustrate the practical applications of immunogenetics in diagnosing, treating, and managing Type 2 Diabetes Mellitus to help bridge the gap between theory and practice and enhance the relevance of the content for healthcare professionals. The book Explore the integration of multi-omics approaches, including genomics, transcriptomics, proteomics, and metabolomics, to provide a comprehensive understanding of the complex interactions between genetic and immunological factors in Type 2 Diabetes Mellitus. This holistic approach can offer insights into novel biomarkers and therapeutic targets. In addition, discussions on the ethical, legal, and social implications of immunogenetics research in Type 2 Diabetes Mellitus, such as genetic privacy, informed consent, and equity in healthcare access. Addressing these considerations is essential for promoting responsible research practices and ensuring equitable healthcare outcomes. The book is essential for seasoned researchers in T2DM, healthcare professionals, or a student entering the field; this book offers invaluable insights into the future of T2DM research and treatment. - Synthesizes the latest research, providing a one-stop resource for researchers to deepen knowledge of genetic variations and immune responses in T2DM in the lab - Integrates findings from diverse studies, helping researchers navigate the complexity of genetic and immune interactions in T2DM - Provides insights into immune-mediated complications in T2DM and their clinical implications - Presents case studies and practical insights for translating research findings into experimental design for personalized patient care

Table of contents

• Title of Book
• 1. Introduction to type 2 diabetes mellitus (T2DM)
• 2. Genetic and epigenetic landscape of type 2 diabetes mellitus
• 3. The immune system and type 2 diabetes mellitus (T2DM)
• 4. Immune cells and T2DM
• 5. Cytokines and insulin sensitivity
• 6. Genetic variations influencing immune response
• 7. Gene-environment interaction in type 2 diabetes mellitus (T2DM)
• 8. HLA associations in T2DM susceptibility
• 9. Immune-mediated complications in type 2 diabetes mellitus (T2DM)
• 10. Targeting immune pathways for T2DM treatment
• 11. Personalized medicine approaches based on immunogenetic profiling
• 12. Emerging trends in immunogenetic research in type 2 diabetes mellitus (T2DM)
• 13. Unresolved questions and challenges in immunogenetics
• 14. Integrating immunogenetics in T2DM research and practices
• 15. Genetics and immunity: Mapping pathways in type II diabetes (T2D)
• 16. Antibody-based therapies for type 2 diabetes mellitus (T2DM)
• 17. Targeting inflammatory pathways in T2DM: Therapeutic interventions
• Index