The advancement and application of process analytical technology (PAT) in pharmaceutical manufacturing represents a complex task, requiring an understanding of both historical developments and modern technological methods. This book provides a comprehensive overview of the current use of various analytical tools and methods within the industry and how they can be applied to PAT. It covers topics such as sampling innovation, statistical process control, and the utilization of chemometrics, all pivotal for maintaining and improving product quality. The text delves into methods like near-infrared spectroscopy, Raman spectroscopy, and spectrophotometry, discussing their principles, applications, and benefits in real-time monitoring and process control. It provides an insight into the continuous manufacturing of solid oral dosage forms, highlighting regulatory considerations and the integration of PAT for enhanced product quality and efficiency. Furthermore, the book explores the role of sensors, liquid chromatography, and mass spectrometry as essential components in monitoring and optimizing manufacturing processes. Unique to this book are the practical examples and case studies that illustrate the implementation of PAT tools across different phases of pharmaceutical development. This makes it an invaluable resource for pharmaceutical scientists, engineers, and technicians, as well as researchers and advanced students in related fields, offering direct insights into innovative practices and the future direction of pharmaceutical manufacturing.
eBook - ePub
Process Analytical Technology in Pharma
Foundations for the Analytical Scientist
- 752 pages
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Process Analytical Technology in Pharma
Foundations for the Analytical Scientist
About this book
Information
Table of contents
- Cover Page
- Half Title Page
- Series Page
- Title Page
- Copyright Page
- Contents
- Preface
- 1 From Benchtop to Manufacturing…
- 2 Sampling the Critical “Before Analysis” Domain
- 3 Optimizing Good Pharmaceutical Practice through Statistical Process Control
- 4 Chemometrics for PAT
- 5 Continuous Manufacturing of Small Molecule Solid Oral Dosage Forms
- 6 Sensors in PAT
- 7 Process NIR
- 8 The Use of Raman Spectroscopy in Pharmaceutical PAT
- 9 Process Spectrophotometry
- 10 Online HPLC as a Process Analytical Technology
- 11 Benchtop NMR in Process Analytical Technology
- 12 Process Headspace Monitoring
- 13 Process Mass Spectrometry
- 14 Process FBRM
- 15 Terahertz Spectroscopy in Tablet Manufacturing
- 16 Process Analytical Technology in Bioprocessing
- 17 Method Validation and Transfer
- 18 Regulatory Consideration for PAT
- Index
Trusted by 375,005 students
Access to over 1.5 million titles for a fair monthly price.
Study more efficiently using our study tools.
Frequently asked questions
Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription
No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn how to download books offline
Perlego offers two plans: Essential and Complete
- Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
- Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.5M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1.5 million books across 990+ topics, we’ve got you covered! Learn about our mission
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more about Read Aloud
Yes! You can use the Perlego app on both iOS and Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app
Yes, you can access Process Analytical Technology in Pharma by Gregory K. Webster,Greg D. Doddridge,Laila Kott in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Analytic Chemistry. We have over 1.5 million books available in our catalogue for you to explore.