- 176 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Rapid Cell Magnetisation Using Cationised Magnetoferritin
About this book
Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.
Information
Table of contents
- Supervisor’s Foreword
- Abstract
- Acknowledgements
- Contents
- Abbreviations
- 1 Introduction
- 2 Materials and Methods
- 3 Characterising Magnetoferritin and Cationised Magnetoferritin
- 4 Stem Cell Labelling with Cationised Magnetoferritin
- 5 Toxicological Profiling of Cationised Magnetoferritin
- 6 Escherichia coli Labelling with Cationised Magnetoferritin
- 7 Overall Conclusions and Future Opportunities
- Appendix A: List of Naturally Occurring Amino Acids
- Appendix B: Background Subtraction with the MPMS
- Appendix C: Adipo- and Osteogenesis of Untreated hMSCs
- Appendix D: Unstained and H&E Stained Cartilage Sections
- Curriculum Vitae
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Yes, you can access Rapid Cell Magnetisation Using Cationised Magnetoferritin by Sara Correia Carreira in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biology. We have over 1.5 million books available in our catalogue for you to explore.