- 475 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Phosphodiesterases: CNS Functions and Diseases
About this book
PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis. This family of enzymes also plays a role in diseases and disorders of the CNS such as depression, anxiety, schizophrenia, and Alzheimer's Disease. Unfortunately no effective PDE inhibitors have been developed for the treatment of these diseases. The proposed book will be a comprehensive overview of the current state of basic and translational research on PDE inhibitors written by internationally recognized experts. Authors will also discuss potential PDE subtypes and splice variants in the hopes that this will spur more creative approaches to PDE targeting drugs.
Information
Table of contents
- Foreword
- About the Editors
- Preface
- Contents
- Contributors
- Part I: PDEs and Signaling, Circuitry, and Implications of CNS Functions and Disorders
- Part II: PDEs in Cognition of Aging and Alzheimer’s Disease
- Part III: PDEs in Parkinson’s and Huntington’s Diseases
- Part IV: PDEs and Psychiatric Disorders
- Part V: PDEs and Others
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Yes, you can access Phosphodiesterases: CNS Functions and Diseases by Han-Ting Zhang,Ying Xu,James M. O'Donnell in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Neuroscience. We have over 1.5 million books available in our catalogue for you to explore.