This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.
- 153 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Resistance to Molecular Therapies for Hepatocellular Carcinoma
Table of contents
- Dedication
- âResistance to Targeted Anti-Cancer Therapeuticsâ: Aims and Scope
- About the Editor
- Preface
- Contents
- Tumor Heterogeneity and Resistance to Targeted Therapies in Hepatocellular Carcinoma
- Modulating Immune Responses to Overcome Resistance in Hepatocellular Carcinoma
- Role of Tumor Microenvironment in Hepatocellular Carcinoma Resistance
- Contribution of the Cancer Stem Cell Phenotype to Hepatocellular Carcinoma Resistance
- Clinical and Preclinical Perspectives on Mechanisms of Sorafenib Resistance in Hepatocellular Carcinoma
- Radiological Assessment of Response to Palliative Treatments in Hepatocellular Carcinoma
- Sorafenib and Clinical Patterns of Resistance in Hepatocellular Carcinoma
- Overcoming Treatment Resistance in Hepatocellular Carcinoma: Regorafenib and Lessons from Other Malignancies
- Index
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Yes, you can access Resistance to Molecular Therapies for Hepatocellular Carcinoma by Augusto Villanueva in PDF and/or ePUB format, as well as other popular books in Medicine & Oncology. We have over 1.5 million books available in our catalogue for you to explore.