The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, differs between the two models, with the 3D system being better able to emulate the in vivo behaviour of neural networks. The book offers an extensive analysis of the system, from the theoretical background, to its design and applications in neuro-pharmacological studies. Moreover, it includes a concise yet comprehensive introduction to both 2D and 3D neuronal networks coupled to MEAs, and discusses the advantages, limitations and challenges of their applications as cellular and tissue-like in vitro experimental model systems.
- 151 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems
About this book
Information
Table of contents
- Part of this thesis have been published in the following articles:
- Supervisor’s Foreword
- Acknowledgments
- Contents
- About the Author
- 1 Introduction
- Scientific and Technical Background
- 2 Dissociated Neuronal Networks Coupled to Micro-Electrode Arrays Devices
- 3 In Vitro Neuronal Networks
- A New In Vitro Model: 3D Neural Networks Coupled to MEA Devices
- 4 3D Neuronal Networks: State of the Art
- 5 3D Neuronal Networks Coupled to MEAs
- Additional Applications with MEA Technology
- 6 Neuro-Pharmacological Studies
- Discussion and Conclusion
- 7 Conclusion of the Thesis and Future Perspectives
- Appendix: Data Analysis
Trusted by 375,005 students
Access to over 1.5 million titles for a fair monthly price.
Study more efficiently using our study tools.
Frequently asked questions
Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription
No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn how to download books offline
Perlego offers two plans: Essential and Complete
- Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
- Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.5M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.
We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1.5 million books across 990+ topics, we’ve got you covered! Learn about our mission
Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more about Read Aloud
Yes! You can use the Perlego app on both iOS and Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app
Yes, you can access Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems by Monica Frega in PDF and/or ePUB format, as well as other popular books in Technology & Engineering & Cell Biology. We have over 1.5 million books available in our catalogue for you to explore.