Real-World Research to Improve Dementia Care

Embedding Pragmatic Trials of Non-Drug Interventions

Jill Harrison, Vincent Mor

• Publisher: Academic Press
• Year: 2026
• eBook ISBN:
  9780443407017
• Topic: Medicine
• Subtopic: Neurology

Real-World Research to Improve Dementia Care: Embedding Pragmatic Trials of Non-Drug Interventions addresses the urgent need for effective care strategies for the over 50 million individuals living with Alzheimer's disease and related dementias. This insightful book introduces embedded, pragmatic trials as a way to bridge the gap between clinical research and everyday practice, emphasizing collaboration among healthcare systems, researchers, and communities. Through a series of chapters, the book explores partnership strategies, ethical considerations, and the selection of meaningful outcome measures, all aimed at enhancing dementia care. The authors present case studies that showcase successful interventions and innovative practices across care settings.By highlighting both the challenges and solutions in dementia care, this book serves as a vital resource for healthcare professionals and researchers. It advocates for a compassionate approach that values the voices of individuals living with dementia, ultimately aiming to improve their quality of life. - Explores innovative case studies that demonstrate successful interventions in dementia care across diverse settings - Guides researchers and on community partners to facilitate collaborative research aimed at improving outcomes for individuals with dementia - Covers the ethical and regulatory challenges unique to conducting research involving vulnerable populations - Identifies effective measures that resonate with the experiences and needs of people living with dementia and their caregivers - Presents emerging technologies that promise to transform dementia research and care practices for the future

Table of contents

• Title of Book
• Chapter 1. Introduction to embedded pragmatic trials to improve dementia care
• Chapter 2. Partner engagement as a foundation for embedded dementia research
• Chapter 3. Approaches to key design features for ePCTs in dementia care
• Chapter 4. Selecting measures that matter to people living with dementia and care partners
• Chapter 5. Anticipating and addressing ethical and regulatory challenges in embedded pragmatic trials involving people living with dementia
• Chapter 6. Building research and community partnerships in home healthcare and hospice to conduct pragmatic trials
• Chapter 7. Implementing interventions to improve dementia care: Understanding mechanisms of action in embedded pragmatic clinical trials in home and community settings
• Chapter 8. Future directions for pragmatic trials in non-drug interventions for dementia care
• Chapter 9. Case studies of embedded pragmatic trials: How pragmatic?
• Chapter 10. Music & memory: Lessons from an embedded, cluster-randomized pragmatic trial to reduce agitation in nursing home residents with dementia
• Chapter 11. Addressing fragmented care for people living with dementia: Lessons learned from embedding a pragmatic clinical trial in an accountable care organization
• Chapter 12. Piloting a pragmatic trial of Tele-Savvy: An online dementia caregiver psycho-education program
• Chapter 13. Implementation of dementia-friendly and age-friendly health system programs across settings of care
• Chapter 14. Interventions to reduce acute care transfers (INTERACT): Large-scale research partnerships within long-term care communities
• Chapter 15. An embedded pragmatic clinical trial of the individualized positive psychosocial interaction program: A comprehensive case study in nursing homes
• Chapter 16. Pragmatically designed cluster-randomized trials of influenza vaccine strategies in nursing homes
• Chapter 17. Detection of dementia in the emergency department
• Chapter 18. ALIGN: Case study of deprescribing in people with dementia
• Chapter 19. Lessons learned from the Protect Trial: A pragmatic cluster-randomized trial of universal decolonization in nursing homes to reduce infection, hospitalizations, and multidrug-resistant organisms (MDROs)
• Index