Prions in Humans and Animals
eBook - PDF

Prions in Humans and Animals

  1. 741 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Prions in Humans and Animals

About this book

Dieses umfassende Werk in englischer Sprache richtet sich gleichermaßen an Studenten und Forscher. Es behandelt systematisch alle Aspekte der Prionenkrankheiten, von ihrer Geschichte, Mikrobiologie und Pathologie bis hin zu Übertragungswegen und möglicher Prävention. Das Buch beschreibt Krankheiten wie Creutzfeld-Jakob-Krankheit, Kuru, Rinderwahn (BSE) und Scrapie, unter besonderer Berücksichtigung der biochemischen, molekularbiologischen, genetischen und klinischen Aspekte. Eine genaue Beschreibung der Wirkung von Prionenkrankheiten im Bereich der Pharmazie, bei Blutprodukten, Desinfektion, chirurgischen Instrumenten und der Epidemiologie rundet das Werk mit einer Diskussion über präventive Maßnahmen ab.

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Yes, you can access Prions in Humans and Animals by Beat Hörnlimann, Detlev Riesner, Hans A. Kretzschmar, Beat Hörnlimann,Detlev Riesner,Hans A. Kretzschmar in PDF and/or ePUB format, as well as other popular books in Medicine & Clinical Medicine. We have over one million books available in our catalogue for you to explore.

Information

Publisher
De Gruyter
Year
2009
Print ISBN
9783110182750
eBook ISBN
9783110200171
Edition
1
Topic
Medicine
Subtopic
Clinical Medicine

Table of contents

  1. Frontmatter
  2. Table of Contents
  3. Abbreviations
  4. 1. Historical Introduction
  5. 2. History of Kuru Research
  6. 3. History of Prion Research
  7. 4. The Physical Nature of the Prion
  8. 5. Folding of the Recombinant Prion Protein
  9. 6. Structural Studies of Prion Proteins
  10. 7. Function of Cellular Prion Protein (PrPC) in Copper Homeostasis and Redox Signaling at the Synapse
  11. 8. The Scarpie Isoform of the Prion Protein PrPSe Compared to the Celluar Isoform PrPC
  12. 9. The Phylogeny of Mammalian and Nonmammalian Prion Proteins
  13. 10. Knockouts and Transgenic Mice in Prion Research
  14. 11. Transplantation as a Tool in Prion Research
  15. 12. Prion Strains
  16. 13. Portrait of Kuru
  17. 14. Portrait of Creutzfeldt-Jakob Disease
  18. 15. Portrait of Variant Creutzfeldt-Jakob Disease
  19. 16. Portrait of Gerstmann-Sträussler-Scheinker Disease
  20. 17. Portrait of Fatal Familial Insomnia and Sporadic Fatal Insomnia
  21. 18. Portrait of Scrapie in Sheep and Goat
  22. 19. Portrait of Bovine Spongiform Encephalopathy in Cattle and Other Ungulates
  23. 20. Portrait of Prion Diseases in Zoo Animals
  24. 21. Portrait of Chronic Wasting Disease in Deer Species
  25. 22. Portrait of Transmissible Mink Encephalopathy
  26. 23. Portrait of Transmissible Feline Spongiform Encephalopathy
  27. 24. Portrait of Experimental BSE in Pigs
  28. 25. Portrait of a Spongiform Encephalopathy in Birds and the Transmissibility of Mammalian Prior Diseases to Birds
  29. 26. Pathology and Genetics of Human Prion Diseases
  30. 27. The Pathology of Prion Diseases in Animals
  31. 28. Pathophysiology of Prion Diseases Following Peripheral Infection
  32. 29. Introduction of Surveillance for Human Prion Diseases
  33. 30. Clinical Findings in Human Prion Diseases
  34. 31. Methods for the Clinical Diagnosis of Human Prion Deseases
  35. 32. Introduction to Surveillance for Animal Prion Diseases
  36. 33. Clinical Findings in Bovine Spongiform Encephalopathy
  37. 34. Clinical Findings in Scrapie
  38. 35. Diagnosis of Bovine Spongiform Encephalopathy by Immunological Methods
  39. 36. Epidemiology and Risk Factors of Creutzfeldt-Jakob Disease
  40. 37. Creutzfeldt-Jakob Disease in Germany
  41. 38. The Epidemiology of Kuru
  42. 39. The Course of the BSE Epidemic - Retrospective Epidemiological Considerations
  43. 40. The Causes of the BSE Epidemic
  44. 41. The Experimental Transmissibility of Prions and Infectivity Distribution in the Body
  45. 42. Iatrogenic and "Natural" Transmissibility of Prion Diseases
  46. 43. Inactivation in Practice - Risk Assessment and Validation for Food Gelatin
  47. 44. Chemical Disinfection and Inactivation of Prions
  48. 45. Thermal Inactivation of Prions
  49. 46. Prevention of Prion Diseases in the Production of Medicinal Products, Medical Devices, and Cosmetics
  50. 47. Prevention of the Transmission of Prion Diseases in Healthcare Settings
  51. 48. Precautionary Measures for Autopsies Performed in Cases of Suspected Prion Disease
  52. 49. Prevention of Prion Diseases in Research Laboratories
  53. 50. Evidence for a Link between Variant Creutzfeldt-Jakob Disease and Bovine Spongiform Encephalopathy
  54. 51. Risk Assessment of Transmitting Prion Diseases through Blood, Cornea, and Dura Mater
  55. 52. BSE Risk Assessment and Minimization
  56. 53. BSE Control - Internationally Recommended Approaches
  57. 54. Atypical Scrapie-Nor98
  58. 55. Scrapie Control - Internationally Recommended Approaches
  59. 56. The PrP Genotype as a Marker for Scrapie Susceptibility in Sheep
  60. 57. Scrapie control at the National level: The Norwegian Example
  61. Backmatter