Vitamin D

Molecular, Cellular and Clinical Endocrinology. Proceedings of the Seventh Workshop on Vitamin D, Rancho Mirage, California, USA, April 1988

A. W. Norman, K. Schaefer, H. G. Grigoleit, D. von Herrath, A. W. Norman, K. Schaefer, H. G. Grigoleit, D. von Herrath

• Publisher: De Gruyter
• Year: 2011
• Print ISBN: 9783110114775
• eBook ISBN: 9783110846713
• Edition: 1
• Topic: Biological Sciences
• Subtopic: Biochemistry
• Index: Biological Sciences

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Table of contents

• Chemistry of Vitamin D Seco-Steroids
• Development of Synthetic Methods for Fluorinated Vitamin D Analogs
• Vitamin D Analogues: Potential Inhibitors of Vitamin D Metabolism
• Synthesis of 26,27-Hexadeutero and Epimeric 26-Trideutero 1,25-Dihydroxycholecalciferols
• Chemical Synthesis of Vitamin D Analogs with Selective Biological Activities
• Chemistry of Vitamin D, its Metabolites and Analogs
• A Practical Synthesis of 1-Alpha-OH Vitamin D3 Analogs
• Synthesis of Biologically Active Cyclopropane Analogues of 1α, 25-Dihydroxy- and 1α-Hydroxy-Vitamin D3
• Asymmetric Synthesis of 1α, 25-Dihydroxyvitamin D3 and Analogs
• Chemical Synthesis and Studies of 9(11)-Dehydrovitamin D and its 11-Substituted Analogues
• A- and C-Ring Modified Vitamin D Analogues: A Mechanistic Study of the [1,7]-Sigmatropic Hydrogen Shift of the Previtamin D-Vitamin D Equilibrium
• Synthesis and Biologic Evaluation of a Second Generation Photoaffinity Analog of 1,25-Dihydroxyvitamin D3
• Synthesis of the Unnatural (7Z)-Vitamin D Triene System
• Novel and Stereoselective Syntheses of 1α-Hydroxylated Vitamin D Metabolites
• On Oxidation of the Vitamin D Triene System – A Simple and Convenient Entry into the 19-Nor-10-Oxo-Derivatives of Vitamin D
• Synthesis of 25-Hydroxydihydrotachysterol2
• Stereochemistry at C(23) of 23,25-Dihydroxy-24-Oxovitamin D3
• Synthesis and Biological Activity of Highly Active Vitamin D Analogs: General Approaches to the Synthesis of Biologically Potent Vitamin D Sterols
• Syntheses of Labeled Side Chains of Vitamin D Metabolites and Analogs
• Synthesis of 22-Oxa-, and 20-Oxa-Analogues of Vitamin D3
• Computer Calculations of the Active Conformation of 1,25-Dihydroxy Vitamin D3
• Vitamin D Metabolism and Catabolism
• Precholecalciferol Formation by an Invertebrate, Psammechinus Miliaris
• Species Variation of Vitamin D Metabolism and Action: Lessons to be Learned from Farm Animals
• Metabolism of Vitamin D in Phagocytic Cells
• Extrarenal Production of Calcitriol in Chronic Renal Failure
• Metabolism of 1,25(OH)2D3 in Perfused Duodena from Normal Chicks
• Intestinal Metabolism of 25-Hydroxyvitamin D3: Effect of the X-Linked Hyp Mutation and 1,25-Dihydroxyvitamin D3 Treatment
• Biosynthesis of Water-Soluble Metabolites of 1,25-Dihydroxyvitamin D3 by Osteosarcoma UMR-106
• Conversion of 25-Hydroxyvitamin D3 to 19-Nor-10-Oxo-25-Hydroxyvitamin D3 by Solubilized Chick Kidney Mitochondria and Bovine Serum Albumin
• 24-Oxidation of 1,25-(OH)2D3 by a Human Osteosarcoma Cell Line, U-20S
• The Vitamin D Depletion of Chronic Cholestasis is Independent of the Hepatic Metabolism of Vitamin D3
• Metabolic Clearance Rate and Production Rate of Calcitriol in Uremia. Effects of 25(OH)D Therapy
• Measurement of Production Rate and Metabolic Clearance Rate of 1,25- Dihydroxyvitamin D3 in Conscious Rats Using a Simplified Primed-Infusion Technique
• Metabolism of 1,25(OH)2D3 after Consecutive Dose of 1αOHD3 and 1,25(OH)2D3 in Rats
• 25-Hydroxyvitamin D3 Sulphate in Human Plasma: Observations Using High Performance-Liquid Chromatography and Gas Chromatography-Mass Spectrometry
• The Effect of Vitamin D Status of Vitamin D Metabolism in Chicks
• Identification of a Subset of Dairy Cows that Fail to Produce 1,25-Dihydroxyvitamin D (1,25-(OH)2D) at the Onset of the Hypocalcemia Associated with Parturient Paresis
• The Intact Hepatocyte Hypothesis Applies to the C-25 Hydroxylation of Vitamin D3 in Alcoholic Cirrhosis
• Mechanism of Action of 26,27-Hexafluoro-1,25(OH)2D3
• 1α, 25(OH)2D3-26,23-Lactone is a Major Metabolite of 1α, 25(OH)2D3 under Physiological Conditions
• 25-Hydroxy-24-Oxovitamin D3 is a Natural Metabolite under Physiological Conditions
• Metabolism of 1,25(OH)2D3 after Single Intravenous or Oral Dose of 1αOHD3 and 1,25(OH)2D3 In Rats
• Administration of Pharmacological Amounts of 25(S), 26-Dihydroxyvitamin D3 Reduces 1,25-Dihydroxyvitamin D3 Synthesis
• The Effect of Growth Hormone on the Phosphate and Calcitriol Responses to Dietary Phosphorus Restriction in Man
• The Effect of Glutethimide on Rapidly Reducing the Circulating Concentration of 1,25-Dihydroxy Vitamin D in Hypervitaminosis D
• Biochemistry and Regulation of Hydroxylases
• Current Models for the Study of the Regulation of 25(OH)D3 Metabolism
• Solubilization and Reconstitution of Mammalian 25-OH-Vitamin D3-24 and 1α-Hydroxylase Activities from Pig Mitochondria
• Molecular Characterization of the Iron-Sulfur Protein from the Porcine Kidney Mitochondrial Hydroxylase System
• Normal Regulation of Calcitriol Production in Gy-Mice: Evidence for Biochemical Heterogeneity in the X-Linked Hypophosphatemic Diseases
• Regulation of 25-Hydroxyvitamin D3 Metabolism in Mitochondria Isolated from Primary Cultures of Chick Kidney Cells: Effects of Parathyroid Hormone and Forskolin
• The Stimulation of 25-Hydroxyvitamin D-1-Hydroxylase by Dietary Phosphorus Restriction Requires Insulin-Like Growth Factor-I (IGF-I)
• Phorbolic Ester Effect on Rat Renal 25-OHD3 1-Hydroxylase Activity: Possible Role of Ca, Phospholipid-Dependent Proteinkinase
• In Vitro Measurement of 25-Hydroxyvitamin D-1-Hydroxylase (1-OHase) Activity in Lactating Mice Using a New, Commercially Available Assay
• Inhibition of Renal Mitochondrial 25(OH)D-1-Hydroxylase Activity by Phosphorylation of Ferredoxin
• Protocol for Partial Purification of the Cytochrome P-450-1α
• Purification of a Cytochrome P-450 from Rabbit Liver Mitochondria Catalyzing 25-Hydroxylation of Vitamin D3
• Acute Changes in Perfusate Calcium and Phosphorus do not Affect 1-α-Hydroxylase Activity in the Isolated Perfused Rat Kidney
• Does the Administration of Phosphate Increase the Serum 1,25(OH)2D Concentration in X-Linked Hypophosphatemic Rickets?
• Ascorbic Acid Effects on 1-OHase and 24-OHase Activity in Kidney and 1,25(OH)2D3 Receptor Binding in Intestinal Mucosa of Guinea-Pigs
• Metabolism in Vitro of 25-Hydroxyvitamin D3 by Cultured Porcine Alveolar Macrophages
• Evidence that Rat Kidney 25-Hydroxyvitamin D-24-Hydroxylase Can Exist in an Inactive State
• 25 Hydroxyvitamin D, 1α Hydroxylase (1-OH-Lase) Activity in Rhesus Monkeys
• 25-Hydroxylation of Vitamin D3 by a Cytochrome P-450 from Pig Kidney Microsomes
• Receptors for 1,25(OH)2D3 (Biochemistry and Molecular Biology)
• Vitamin D Hormone Receptors: Structure, Regulation and Molecular Function
• Vitamin D3 Receptors: Molecular Structure of the Protein and its Chromosomal Gene
• Definition of the Funktional Domains of the Vitamin D3 Receptor
• Hyperthyroidism Increases Nuclear 1,25-Dihydroxyvitamin D3 Binding in Female Rat Liver
• Changes in Intestinal 1,25-Dihydroxyvitamin D Receptor Durning Aging, Gestation and Pregnancy in Rats
• Positive Cooperativity of the Rat Intestinal 1,25 Dihydroxyvitamin D Receptor
• Ketoconazole Potentiates 1,25-(OH)2D3-Directed Upregulation of 1,25-(OH)2D3-Receptors in Rat Intestine and Bone
• 1α, 25-Dihydroxyvitamin D3 Receptor Defects in Lymphocyte Cell Lines from Vitamin D-Dependent Rickets Type II
• Vitamin K Role in the Interaction of 1,25(OH)2D3 Receptors with DNA
• Administration of 1,25-Dihydroxyvitamin D3 (1,25-(OH)2D3) Upregulates Number of Receptors for 1,25-(OH)2D in Colon Mucosa of Dairy Cows
• Characterization of the Chromosomal Gene of the Mouse Vitamin D Receptor
• Regulation of Vitamin D Action in Rat Osteogenic Sarcoma Cells (UMR-106)
• Duodenum and Colon 1,25-Dihydroxyvitamin D (1,25-(OH)2D) Receptor Concentration is Increased During Lactation in the Rat
• The 1,25-Dihydroxycholecalciferol Level in Plasma does not Influence the Properties of its Intestinal Receptor in Piglets
• The Number of 1,25-Dihydroxyvitamin D Receptors in Rat Intestinal Mucosa have been Markedly Underestimated
• DNA Binding Property of Vitamin D3 Receptors Associated with 26,26,26,27,27,27-Hexafluoro-1,25(OH)2D3
• Vitamin D3 Binding Protein of Phaseolus Vulgaris Roots. Biochemical and Functional Characterization
• Cell Differentiation / Hematopoiesis / Immunology
• Interaction between the Hematopoietic System and the Vitamin D Endocrine System
• 1,25-(OH)2D3 and Gene Expression During HL-60 Differentiation
• Vitamin D: A Steroid Hormone of the Immune System, by the Immune System, for the Immune System
• Immunoregulatory Properties of 1,25(OH)2D3: Cellular Requirements and Mechanisms
• 1,25-Dihydroxyvitamin D3 and the Regulation of Cancer Cell Replication
• MC 903 – A Novel Vitamin D Analogue with Potent Effects on Cell Proliferation and Cell Differentiation
• 1α, 25-Dihydroxy-22-Oxavitamin D3: A New Synthetic Analogue of Vitamin D3 Having Potent Differentiation-Inducing Activity without Inducing Hypercalcemia in Vivo and in Vitro
• Mechanisms of Cell Fusion Induced by 1α,25-Dihydroxyvitamin D3
• 1,25(OH)2D3 Promotes Differentiation of Resting Chondrocytes to Hypertrophic Cells in Vitro: A Model System for Evaluating the Potency of Vitamin D Analogs
• 1α,25-Dihydroxyvitamin D3 Synthesis by Synovial Fluid Macrophages in Arthritic Disease
• 1,25-Dihydroxyvitamin-D3 Prolongs Rat Cardiac Allograft Survival
• 1,25-Dihydroxyvitamin D3 as a Synergistic Agent of in Vitro Cyclosporin A-Induced Suppressive Activity in Rheumatoid Arthritis
• Changes in Phosphoinositide Metabolism During 1,25(OH)2D3 Induced Cell Differentiation
• Increase in [Ca2+]i in Cultured Human Keratinocytes by 1,25(OH)2D3 is Calcium Dependent and Coincides with an Increase in Phosphatidylinositol Metabolism
• The Effects of 1α,25(OH)2D3, Diltiazem (D-Cis, L-Cis) on Induction of Differentiation of HL-60 Cells
• 1α-Hydroxylated Vitamin D Metabolites Promote Differentiation and 24,25-Dihydroxy Vitamin D Synthesis in Human Leukaemia (HL60) Cells
• 1,25 Dihydroxyvitamin-D3 Prolongs Skin Graft Survival in Mice
• Effects of 1,25(OH)2D3 on Myelopoiesis and B Lymphopoiesis in Long-term Marrow Cultures
• Vitamin D-Deficiency Disturbs the Differentiation Process in the Dental Papilla: An Ultrastructural Study
• 1,25-Dihydroxyvitamin D3 Inhibits Delayed-Type Hypersensitivity Mediated by T-Cell Clones Inducing Experimental Autoimmune Encephalomyelitis
• 1,25-Dihydroxyvitamin D3 Acts Directly on Human Lymphocytes and Interferes with the Cellular Response to Interleukin-2
• 1α,25-Dihydroxyvitamin D3 Synthesis by Normal and Myelofibrotic Human Spleen Cells
• Pretreatment of T Cell or Monocytic Cell Lines with 1,25(OH)2D3 Markedly Increases IL2 or IL1 mRNA Levels Following Cell Activation
• Phorbol Ester Stimulation of 25OH-Vitamin D 1-Hydroxylase Activity in the Monoblastic Cell Line U937
• An Evaluation of Analogs of 1,25-Dihydroxyvitamin D3 on the Inhibition of Proliferation and Induction of Terminal Differentiation in Cultured Human Normal Keratinocytes
• 1,25-Dihydroxyvitamin D3 Potentiates the Immunomodulatory Action of Prostaglandin E2 and Histamine by Interacting with cAMP-Dependent Pathways
• Effects of 1,25-Dihydroxyvitamin D3 and other Steroid Hormones on Protein Syntheses in Primary Cultures of Adult Rat Hepatocytes
• The Separation of Keratinocyte Populations Using a Gravity Sedimentation Chamber: A Potential Tool for the Study of 1,25(OH)2D3 Action on Cells at Different Stages of Differentiation
• Evidence that Osteoinduction by Implants of Demineralized Allogenic Bone Matrix is Diminished in Vitamin D-Deficient Normocalcemic Rats R. T. Turner, J. J. Vandersteenhoven, ?. H. Bell
• 1,25(OH)2D3 Binds Specifically to Rat Vascular Smooth Muscle Cells and Stimulates their Proliferation in Vitro
• Involvement of Intracellular Free Calcium and pH in the Effect of 1,25(OH)2D3 on Leukemic Cells
• Gene Regulation by 1,25(OH)2D3
• Modifications in the Interactions of Regulatory Proteins with the Promoter of a Cell Growth Regulated Gene Induced to Differentiate by 1,25(OH)2D3
• Inhibition of 1,25-Dihydroxyvitamin D3 Stimulated BGP mRNA Synthesis in ROS 17/2 Cells after Prolonged Treatment with 1,25-Dihydroxyvitamin D3
• 1,25(OH)2D Regulates Oncogene Expression in U937 Cells
• Regulation of Calbindin-D9K (CaBP9K) Gene Expression by 1,25-Dihydroxycholecalciferol and Calcium in Organ Cultures of Fetal Rat Duodenum
• Enhancement of the Genomic Action of 1,25-Dihydroxycholecalciferol by Triiodothyronine is a Regulatory Factor of Intestinal Calcium and Phosphate Transport
• Influence of Vitamin D3 upon the Expression of PEP-19, a Putative Neuron-Specific Calcium-Binding Protein
• Induction of Osteocalcin Synthesis in Human Osteosarcoma Cells by 1,25-Dihydroxyvitamin D and 24,24-Difluoro-1,25-Dihydroxyvitamin D
• Biological Actions of Vitamin D Metabolites
• The Role of 24,25 Dihydroxy Vitamin D3 During Development of Skeletal and Non-Skeletal Tissues
• The Regulation of Intracellular Ionized Calcium by Calcitriol
• Rapid Action of 1,25(OH)2D3 in Liver Cells
• 1,25(OH)2D3 directly Modulates Human Melanocyte Function
• Stimulation of Synthesis of Myoblast Membrane Proteins by 25-Hydroxy- Vitamin D3
• Stimulation of Rat Duodenal Brush Border Alkaline Phosphatase Activity within 10 Minutes of in Vivo Calcitriol Administration
• 1,25-Dihydroxy-Vitamin D3 Increases 3H-Thymidine-Uptake and Potentiates the Effect of Epidermal Growth Factor in FRTL-5 Cells
• 1,25-Dihydroxyvitamin D3 Stimulates 45Ca2+ Uptake by Cultured Vascular Smooth Muscle Cells Derived from Rat Aorta
• 1,25(OH)2D3 Activates Protein Kinase C in Rat Colonic Crypts
• Free 1,25-Dihydroxyvitamin D3 Levels in Normal and Rachitic Piglets
• 1,25(OH)2 Vitamin D3 Analogs: Comparison of 1,25(OH)2D3 Receptor Ligand Specificity and Biological Activity in the Chick and Human Promyelocyte (HL-60) Cells
• 24,25-Dihydroxy-Vitamin D3 Binding in Bovine Thyroid
• Effects of 1,25-Dihydroxy-Vitamin D3 on Phospholipid Metabolism in Cultured Myoblasts
• Vitamin D Status and Intestinal Absorption of Aluminum in Rats with Normal or Reduced Renal Function
• Direct Effect of Vitamin D Metabolites on Matrix Vesicle Alkaline Phosphatase
• Proliferative Effects of 1,25-Dihydrocholecalciferol (1,25-DHCC), 24,25-Dihydroxycholecalciferol (24,25-DHCC), 25-Hydroxycholecalciferol (25-HCC) and 1α-Hydroxycholecalciferol (1α-HCC)
• The Effect of Pertussis Toxin on PTH- and 1α,25(OH)2D3-Induced Desensitization in Rat Osteoblasts of the cAMP Response to PTH
• Synergistic Effects of Vitamin D3 Metabolites
• 25(OH)D3, but not 1,25(OH)2D3 Cures Osteomalacia in Marmoset Monkeys
• Acute Release of Bioactive PTH by Intravenous 1,25 Dihydrocholecalciferol in Chronic Renal Failure
• 1,25-Dihydroxy-Vitamin D3 Increases Calmodulin Binding to Skeletal Muscle Membrane Proteins
• Hypoparathyroidism in Hereditary Resistance to 1,25(OH)2D During Long-Term Treatment with Excessive Doses of Vitamin D3
• Effects of 1-alpha-OHD3 in Intestinal Radiocalcium Absorption and Serum Bone GLA Protein in Normal Subjects and Osteoporotic Women R. Nuti, V. Turchetti, G. Martini, G. Righi, F. Loré, A. Caniggia
• Rapid Effects of 1,25(OH)2-Vitamin D3 on Calcium Uptake by Cardiac Muscle
• 1α, 25-Dihydroxyvitamin D3 in Rat Skin: Identification, Quantification and Biological Function
• 1,25-Dihydroxyvitamin D3 Stimulates Ca-ATPase and Regulates Cellular Calcium in Vascular Smoosth Muscle Cells
• Calbindins (Biochemistry, Molecular Biology, Biological Actions)
• Calbindin-D9K (CaBP9K) Gene: Expression, Regulation, Structure and Evolution
• 1,25-Dihydroxyvitamin D3, its Receptor and the Eukaryotic Genome
• Structure and Evolution of the Chick Calbindin Gene
• Regulation of Rat Calbindin-D28k Gene Expression
• Molecular Cloning and Sequencing of Calbindin-D9K cDNA from Mouse Placenta
• High Conservation of Calbindin D28 in Evolution: Implications for its Function
• Functional Analysis of the Promotor Region of the Gene Encoding Chicken Calbindin-D28K
• Cellular Localization of Brain Calbindin-D28k
• Vitamin D Dependence of Calbindin D 9K and Calbindin D 28K Synthesis in Various Rat Tissues
• Immunohistochemical Demonstration of Vitamin D-Dependent Calcium-Binding Protein, Calbindin-D 28K (CaBP28K) in the Spinal Cord Motoneurons of Teleost Fish
• In Situ Hybridization of the Rat Calbindin D-28
• Spectroscopic Studies on Chick Intestinal Calbindin-D28K Suggest the Existence of 4-6 Functional Ca2+ Binding Sites
• Evolution of the “EF-Hand” CaBP Family: Exon Shuffling and Intron Insertion
• Effects of Altered Thyroid States and Undernutrition on Calbindin-D28K (Calcium-Binding Protein) in the Hippocampal Formation of the Developing Rat
• Expression of Calbindin D Decreases with Age in Intestine and Kidney
• Evidence for Tissue-Specific Regulation of Calbindin 28K Gene Expression in the Chick by 1,25-Dihydroxyvitamin D3
• Evidence for the Presence of two Vitamin D-Dependent Calcium Binding Proteins in Brain
• The Human Calbindin D28 Gene
• Effect of Vitamin D Deficiency and 1,25-Dihydroxycholecalciferol Treatment on Epidermal Calcium Binding Protein (ECaBP) RNA Activity
• Complete Amino Acid Sequences of Mouse Calbindin-D9K Isoforms Determined by Tandem Mass Spectrometry: Protein Modification by Internal Insertion of a Single Amino Acid
• Developmental Pattern and Vitamin D-Dependency of the Calbindins CaBP 9KDa and CaBP 28KDa in the Ameloblasts of Rodent Teeth: An Immunocytochemical Study
• Calbindin (CaBP28kDa) Localization in the Peripheral Vestibular System of Various Vertebrates and Comparison with its Distribution During Development of the Mouse and Human
• Nuclear Magnetic Resonance and Terbium Fluorescence Studies on the Vitamin D-Dependent 28-Kilodalton Chick Intestinal Calcium-Binding Protein : Evidence for Calcium-Dependent Conformational Change
• Intestinal and Renal Ca and P Transport
• Transcaltachia, Vesicular Calcium Transport, and Microtubule-Associated Calbindin-D28K
• Vitamin D: Effects on Intestinal Calcium Absorption and Peripheral Nerve Function
• ATP-Dependent Ca2+ Pumps in Endoplasmic Reticulum and Plasma Membranes are not Affected by 9kDa Calbindin-D and Vit. D-Deficiency
• Effects of Vitamin D-Deficiency on Different Activities of the Ca2+-Pump in Rat Intestinal Basolateral Membranes
• ATP-Driven Ca2+ Pumps in Duodenal Plasma Membranes and Endoplasmic Reticulum from Piglets with Inherited Rickets
• Effect of 1,25(OH)2D3 on Phosphorus Absorption in Sheep
• Reduced Calcium Absorption in X-Linked Hypophosphatemic Rickets
• Phosphate Transport in the Intestine of the Rat During Early Development: Role of Vitamin D
• The 105kD Calmodulin (CAM) Binding Protein from Intestinal Brush Border Membrane (BBM) is a Calcium Transport Protein
• Bone and Action of Vitamin D Metabolites
• The Role of 1,25-Dihydroxyvitamin D3 in the Generation and Regulation of Osteoclasts
• Vitamin D and Osteoclastogenesis
• Dentin Formation and Plasma Ca Levels in PTX Rats given 1,25(OH)2D3
• Elevated 1,25-Dihydroxyvitamin D3 and Intestinal Calbindin-D9K Levels in the Osteopetrotic Toothless Rat
• Influence of 24-Fluorinated Analogues of 1,25(OH)2D3 on Bone Matrix Formation and Bone Resorption in Vitro
• Modulation of the Action of 1,25(OH)2D3 on the Osteocalcin Production of Human Osteoblast-Like Cells by Agents Affecting Adenylate Cyclase Activity
• Increased Bone Minerals in Vitamin D-Replete Rabbit by the Massive Administration of 24R,25(OH)2D3
• Studies on the Interactions between Retinoic Acid and 1,25(OH)2D3 on Human Bone-Derived Osteoblast-Like Cells
• Immunosuppressive Agent Cyclosporin A and Various Cell Growth Factors Affect Cloned Osteoblastic Cell Line MC3T3-E1 Cells
• 23(S)25(R)-1,25(OH)2D3-26,23-Lactone Stimulates Bone Formation in Vivo
• Side Chain Modifications Increase the Potency of 1,25-Dihydroxy- cholecalciferol (Calcitriol) on Human Bone-Derived Osteoblast-Like Cells
• Activity of Ornithine Decarboxylase in Hard Tissue of Vitamin D-Deficient and -Replete Rats: Effect of 1,25(OH)2D3, Uremia and Aluminum Intoxication
• Production of Bone-Resorbing and Osteoclast-Inducing Factors by Osteoblasts in Organ Culture and Modulation by 1,25(OH)2D3 and other Agonists
• Circulating Osteocalcin in Magnesium Deficiency: Response to 1,25(OH)2D
• 1,25(OH)2D3 Mediates the Effect of Parathyroid Hormone on New Bone Formation in the Rat
• Circulating Osteocalcin and 1,25-Dihydroxyvitamin D Concentrations and Urinary γ-Carboxyglutamic Acid in Healthy Subjects and in Patients with Metabolic Bone Disease
• Regulation of Fibronectin and Collagen Synthesis by 1,25-Dihydroxyvitamin D3
• 1,25-Dihydroxyvitamin D3 Stimulates in Vitro Growth of Avian and Mammalian Cartilage
• Nutritional Aspects of Vitamin D
• Minimal Intravenous Vitamin D Requirement During Parenteral Nutrition in Infancy
• Serum 25(OH)D3 and 1,25(OH)2D3 Levels in Wild and Laboratory-Bred Wood Mice and Bank Voles
• Effect of Acute Ethanol Administration on the Circulating Parameters of Bone Mineral Metabolism
• Plasma 25-OHvitamin D and PTH in the Detection of Osteomalacia in Asian Outpatients
• The Vitamin D Content of Finnish Hospital Diets
• Zinc, Vitamin D and Bone Mass in the Elderly
• The Importance of Vitamin C for Hydroxylation of Vitamin D3 to 1α,25(OH)2D3 and of 24R,25(OH)2D3 to a More Active Metabolite
• Plasma Magnesium in Pigs with Pseudo Vitamin D Deficient Rickets; Type 1
• Sunlight Degradation of Vitamin D3
• Fatty Acid and Calcium Absorption in Rats. Role of Vitamin D
• Clinical Studies on the Mechanism of Acquired Vitamin D Deficiency
• How is Plasma 1,25(OH)2D3 Concentration Regulated by Dietary Calcium?
• Studies of Rickets and its Prevention in Beijing, China
• Vitamin D Binding Proteins
• DBP and AIDS: Fact or Fiction?
• Plasma Vitamin D Binding Protein: Plasma Scavenger Function and Origin of Cell-Surface DBP
• Partial Structure of the Gene for Human Vitamin D-Binding Protein
• A New Interaction between Gc (Vitamin D-Binding Protein) and Unsaturated Fatty Acids
• Two 25-Hydroxycholecalciferol-Binding Proteins in Carp Serum
• HPLC Analysis of the Cyanogen Bromide Digest of Human Serum Vitamin D Binding Protein Photoaffinity Labelled with a 25-Hydroxyvitamin D3 Analog
• Effect of Calcium Ions upon Interactions between Gc (Vitamin D-Binding) Protein and Cibacron Blue
• Partial Purification and Properties of Bat Vitamin D Binding Protein Meropi Cavaleros
• Assay Methodology: Vitamin D and Metabolites
• Measurement of Free Vitamin D Metabolite Levels: Biological and Clinical Significance
• The Assay of Circulating 1,25(OH)2D using Non-End-Capped C18 Silica (C18-OH): Performance and Validation
• Simplified Assays for the Determination of 25-OHD, 24,25(OH)2D and 1,25(OH)2D
• Stable Isotope Dilution Mass Fragmentography for the Measurement of Metabolites of Vitamins D2 and D3 in Human Plasma
• Well Established Physiological Functions are a Prequisite for Introducing Biochemical Parameters
• The Quantification of Serum 25-Hydroxyvitamin D Using a Competitive Protein-Binding Assay after Preliminary Purification
• Changes in Plasma Levels of Vitamin D2, D3 and Their Metabolites after Oral Administration of the Vitamins to Vitamin D-Deficient Rats
• Age-Related Changes in Immunoradiometric PTH and 25-Hydroxy- vitamin D
• Relevance of Long-Term Variation in Vitamin D Metabolite Measurements. Implications for Longitudinal Study Design
• Other Basic Science Topics
• Prospects for the Modelling of Vitamin D Activity in Man
• Isolated Rat Proximal Tubule Cell (PTC) Cultures are cAMP Responsive to Parathyroid Hormone (PTH), Calcitonin (CT), and Prostaglandins (PGE) but not to Vasopressin (VP)
• Lipid Composition of Basolateral Membranes from Rat Enterocytes: Effects of Vitamin D Deficiency
• Possible Origin of Extremely Large Amounts of Vitamin D3 in Some Kinds of Fish Liver
• Hepatotoxic Effects of Aluminium: Implications for Vitamin D Metabolism
• Studies on Kinetics of Previtamin D Formation Reaction, Effects of Irradiation Intensity at 296nm on Previtamin D Formation Zhiren Lu, Yafang Pang, Chengfa Zheng
• Vitamin D Deficiency and Cardiac Function in Isolated Chick Hearts
• Vitamin D Effects on Ca-Stimulated ATPase Activity and Protein Composition of the Rat’s Skeletal Muscle Miofibrills
• The Spontaneously Hypertensive Rat (SHR): A Model of Abnormal Vitamin D Metabolism
• Vitamin D3- and Stigmasterol-Induced Calmodulin Synthesis in Phaseolus Vulgaris Roots is Mediated by Ca+2 and Plant Growth Hormone-Like Mitogenic Stimulation
• A Very Rapid Receptor Mediated Action of 1,25-Dihydroxyvitamin D3: Increase of Intracellular Cyclic GMP in Human Skin Fibroblasts
• Effects of Vitamin D3 Metabolites on Cytosolic Free Calcium in Confluent Mouse Osteoblasts: A Possible Involvement of Protein Kinase C Michèle Lieberherr
• Renal Osteodystrophy
• Plasma Kinetics of Intravenous Calcitriol in Normal and Dialysed Subjects and Acute Effect on Serum nPTH Levels
• Bioavailability of Calcitriol after Oral, Intravenous and Intraperitioneal Doses in Dialysis Patients
• Intravenous Administration of 1α-Hydroxycholecalciferol in Haemodialysed Patients: Dose-Dependent Increase in Circulating 1,25-Dihydroxycholecalciferol
• Ten Years Experience in the Prevention of Renal Osteodystrophy by Vitamin D-Prophylaxis
• Successful Treatment of Renal Osteodystrophy with Keto Acids (KA) and Vitamin D
• Effect of 1,25(OH)2D3 and 24R,25(OH)2D3 on the Accumulation of Aluminum in Bone in Rats with Renal Failure
• The Influence of Vitamins D2 and D3 on Intestinal Calcium Absorption in Patients with Renal Insufficiency and in Dialysis Patients
• 1α(OH)D3 i.v. Suppression of PTH Secretion in Hemodialysis Patients
• Clinical and Biochemical Effects of 1,25-Dihydroxyvitamin D3 Administration in Normal and Renal Impaired Dogs
• Hyper- and Normo- Calcemic Dogs with Chronic Renal Failure: Relations of Serum PTH and Calcitriol to PTG Ca++ Set-Point
• Dietary Intake and Status of Vitamin D and Calcium in Patients with Chronic Renal Failure (CRF) Treated by Haemodialysis (HD) at home
• Osteocalcin (OC) in Adolescents with Advanced Renal Failure
• Osteoporosis
• Long-Term Calcitriol Treatment in Post-Menopausal Osteoporosis: Follow-Up of two Hundred Patients
• Osteoporosis and Vitamin D Metabolism: The State of our Knowledge as of 1988
• The Rationale for Calcitriol Therapy in Osteoporosis
• Calcitriol Therapy in the Management of Osteoporosis
• Alfacalcidol in Prednisone Treatment: Effect on Bone Mineral Content in Lumbar Spine and Femur
• Decrease of Plasma 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) and Loss of Spinal Bone Mass in Women During Treatment with GnRH Agonists
• Effect of 26,27-Hexafluoro-1,25-Dihydroxyvitamin D3 (F6-1,25(OH)2D3) on Osteoporosis Induced by Immobilization Combined with Ovariectomy in the Rats
• Some Biochemical Markers in Distal Fore-Arm and Hip Fractures
• The Short Term Effects of Alfacalcidol in Elderly Osteoporotic Women
• Calcitonin Secretion in Osteoporosis of Turner Syndrome
• Determinants of Calcium Malabsorption in Postmenopausal Osteoporosis
• Sarcoidosis
• Regulated Expression of the Sarcoid Macrophage 25-Hydroxyvitamin D-1-Hydroxylation Reaction
• Accentuated Transpleural Gradient of “Total” and “Free” 1,25-Dihydroxyvitamin D in Patients with Tuberculous Pleuritis
• The Effects of Ketoconazole and Metyrapone on Activated Alveolar Macrophages
• 1,25(OH)2D3 Production by Lung T Lymphocytes from Tuberculosis Patients
• Cancer and Vitamin D
• Treatment of Myelodysplastic Syndrome and AML with 1α Hydroxyvitamin D3
• Nude Mouse Model (CAC-8) of Humoral Hypercalcemia of Malignancy (HHM) with Increased Serum Levels of 1,25-Dihydroxycholecalciferol (1,25(OH)2D): In Vivo and in Vitro Studies
• Effects of Treatment with the Bisphosphonate APD on 1,25-Dihydroxyvitamin D in Patients with Malignant Hypercalcaemia
• Effect of 1α-Hydroxyvitamin D3 on Growth of Nitrosomethylurea-Induced Rat Mammary Tumors
• Diabetes and Vitamin D
• Interaction between Vitamin D, Insulin and Diabetes Mellitus
• Endogenous Diabetes Decreases the Number of 1,25-Dihydroxyvitamin D3 Receptors in both Intestine and Kidney
• Plasma Concentrations of Vitamin D Metabolites in Newly Diagnosed Young Insulin-Dependent Diabetics before and after Insulin Treatment
• The Effect of Hypocalcemia and Vitamin D-Deficiency on Glucose Utilization in Piglets
• Vitamin D-Induced Increase in Calcium Content in Secretory Granules of B Cells Plays a Role in Recovery of Insulin Secretion in Vitamin D-Deficient Rats
• Increase in Insulin Response to Glucagon Following UV-B Irradiation in Healthy Adults
• Gerontology and Vitamin D
• Serum 1,25(OH)2D3 in the Elderly and Osteoporotic Subjects from Southern Italy. A Preliminary Report
• Effect of Age on the Rat Intestinal 1,25(OH)2D3 Receptor
• Effect of Age and 1,25(OH)2D3 on Calcium Uptake in Rat Duodenum Cells
• Low Serum Concentrations of 25-Hydroxyvitamin D, Selenium and Osteocalcin in Finnish Elderly Men
• Response of the Serum Level of 1,25(OH)2D to Restriction of Dietary Phosphorus: Effect of Advanced Age
• Intestinal End-Organ Resistance to 1,25-Dihydroxyvitamin D Stimulation of Calcium Absorption in the Senescent Rat
• Pregnancy/Neonatology
• Serum Vitamin D, 25-OHD, and 1,25(OH)2D, Bone Mineral Content (BMC) and Mineral Homeostasis in Premature Infants Fed High Mineral Premature Formula
• Normal Plasma 1,25(OH)2D3 in a Breast Fed Premature Infant with Early Hypophosphatemic Rickets
• Changes in 1,25-Dihydroxyvitamin D3 Receptor (1,25 DR) Content of Rat Mammary Gland During Pregnancy and Lactation
• Concentration of Vitamin D Metabolites in Amniotic Fluid and Serum During Pregnancy
• 1,25(OH)2D3 and Ostoecalcin Concentrations in Fetuses and Neonates from Rats Fed two Different Calcium-Phosphate Diets
• Intact PTH and Vitamin D Metabolites in Early Neonatal Hypocalcemia
• Other Clinical Topics
• Vitamin D and the Skin: Site of Synthesis, Target Tissue, and New Therapeutic Approach for Psoriasis
• Inborn Errors in Vitamin D Metabolism – Their Contribution to the Understanding of Vitamin D Metabolism
• Vitamin D and Human Antituberculosis Immunity
• Successful Treatment of Psoriasis with Topical Application of the Active Vitamin D3 Analog, 1α,24-Dihydroxycholecalciferol (TV-02)
• Evidence that Alteration of the Vitamin D-Endocrine System in Obesity Results from Vitamin D Deficiency
• Abnormal 1,25(OH)2D3 Receptor Relation of Parathyroid Gland in Lead Intoxication
• Hypocalcemia and Decreased 1,25(OH)2D Blood Levels in Septic Patients
• Serum Vitamin D and Calcium Metabolism in Tuberculosis Patients Resident in two Tropical Environments
• Abnormal Vitamin D Metabolism in Primary Aldosteronism and Experimental Mineralocorticoid Excess
• Vitamin D Metabolites and Intact PTH in Spasmophilia
• Vitamin D Status in Patients with Cystic Fibrosis: Seasonal Variations and the Importance of Vitamin D Supplementation:
• An Epidemiological Association between Vitamin D Deficiency and Tuberculosis
• Conversion of 1α-OHD3 into 1,25(OH)2D3 in Normal Subjects, Cirrhotic Patients and Postmenopausal Osteoporotic Women
• The Role of 1,25-Dihydroxyvitamin D in Salt Sensitive Essential Hypertension: Effects of Calcium Channel Blockade
• Vitamin D3 Induced Glycolic Aciduria in an Experimental Stone Model A. Halabe, N. L. M. Wong, L. Hagen, H. Hughes, R. A. L. Sutton
• Vitamin D Metabolism in Benign Transient Hyperphosphatasaemia
• Serum Calcium can Modulate the Production of 1,25-Dihydroxyvitamin D Independently of PTH in Man
• Age-Dependent Changes of Vitamin D Status and 1,25(OH)2D3 Receptor Expression in Spontaneously Hypertensive (SH) Rats
• Behavioral Changes in Chronically D-Hypervitaminotic Animals
• 1,25-Dihydroxyvitamin D3 is an Effective Therapeutic Agent for the Treatment of Psoriasis Vulgaris and Erythroderma Psoriasis
• Vitamin D, Calcium and Hypertension
• Dietary Vitamin D Level and Mineral (P, Ca) Absorption in Pigs Fed Phytic P Diets
• Effect of Active Vitamin D3 on Enterocytes and Fatty Acid Binding Substance in Microsomal Fraction of Intestinal Mucosa of Rats
• Vitamin D Therapy in Renal Failure – Challenges and Problems for the Future
• Synthesis of 24R,25-Dihydroxyvitamin D3 from Vitamin D2 and Study on Inclusion Complexes of Vitamin D Derivatives with β-Cyclodextrin
• Author Index
• Key Word Index
• Cell Line Index
• Vitamin D Workshop Zoo
• Summary of the Dates and Locations of the Seven Vitamin D Workshops
• Vitamin D Workshop Logo