[PDF] Molecular Mechanisms of Adult Stem Cell Aging by K. L. Rudolph | Perlego
Get access to over 650,000 titles
Start your free trial today and explore our endless library.
Start free trial
Join perlego now to get access to over 650,000 books
Join perlego now to get access to over 650,000 books
Join perlego now to get access to over 650,000 books
Molecular Mechanisms of Adult Stem Cell Aging
Molecular Mechanisms of Adult Stem Cell Aging

Molecular Mechanisms of Adult Stem Cell Aging

K. L. Rudolph
Start free trial
shareBook
Share book
pages
116 pages
language
English
format
ePUB (mobile friendly)
availableOnMobile
Available on iOS & Android

Molecular Mechanisms of Adult Stem Cell Aging

K. L. Rudolph
Book details
Table of contents

About This Book

There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis.Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology.

Read More

Information

Publisher
S. Karger
Year
2010
ISBN
9783805592444
Topic
Medicine
Subtopic
Gastroenterology & Hepatology

Table of contents