Calcium and Bone Disorders in Children and Adolescents

J. Allgrove, N. J. Shaw, J., Allgrove, N.J., Shaw, J. Allgrove, N. J. Shaw

• Publisher: S. Karger
• Year: 2015
• Print ISBN: 9783318054668
• eBook ISBN: 9783318054675
• Topic: Medicine
• Subtopic: Alternative & Complementary Medicine

There has been a rapid expansion of knowledge in the field of paediatric calcium and bone disorders over the past twenty years. Advances have been made in the underlying genetic basis for many conditions in conjunction with progress in bone density and geometry imaging and the development of new treatment options. The 2nd revised edition of 'Calcium and Bone Disorders in Children and Adolescents' presents up-to-date information on many aspects included in the 1st edition such as the physiology, pathology, diagnosis and management of numerous conditions including a chapter of case histories illustrating clinical aspects. New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. Providing a comprehensive update, this book is a useful clinical resource for paediatricians and specialists in endocrinology, metabolic bone disease, nephrology, rheumatology, radiology, orthopaedics and clinical genetics who may be faced with a child with a calcium and/or bone disorder.

Allgrove J, Shaw NJ (eds): Calcium and Bone Disorders in Children and Adolescents. 2nd, revised edition.
Endocr Dev. Basel, Karger, 2015, vol 28, pp 414-420 (DOI: 10.1159/000381572)

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Appendix 1: Explanation of Abbreviations Appearing in Text

Abbreviation	Definition
1,24,25(OH)3D	1,24,25-trihydroxy vitamin D
1,25(OH)2D	1,25-dihydroxy vitamin D
1,25(OH)2D2	1,25-dihydroxy ergocalciferol
1,25(OH)2D3	1,25-dihydroxy cholecalciferol (calcitriol)
24,25(OH)2D	24,25-dihydroxy vitamin D
25OHD	25-hydroxy vitamin D
aBMD	Areal bone mineral density
A&E	Accident and emergency
ACE	Angiotensin-converting enzyme
ACVR1/ALK2	Activin receptor I/Activin-like kinase II
AD	Autosomal dominant
ADH	Autosomal dominant hypocalcaemia
ADHR	Autosomal dominant hypophosphataemic rickets
AED	Anti-epileptic drug
AHO	Albright's hereditary osteodystrophy
AIRE	Autoimmune regulator
ALL	Acute lymphoblastic leukaemia
AMP	Adenosine monophosphate
AN	Anorexia nervosa
APECED	Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy
APS1	Autoimmune polyendocrinopathy type I syndrome
ARHR	Autosomal recessive hypophosphataemic rickets
AVP	Arginine vasopressin
BMAD	Bone mineral apparent density
BMC	Bone mineral content
BMD	Bone mineral density
BMDa	Areal bone mineral density
BMDv	Volumetric bone mineral density
BMP1	Bone morphogenic protein I
BMP2	Bone morphogenic protein II
BMPs	Bone morphogenic proteins
BMT	Bone marrow transplant
BMU	Bone multicellular unit
BP	Bisphosphonate
BPABG	British Paediatric and Adolescent Bone Group
BSP	Bone si...

Table of contents

• Cover Page
• Front Matter
• Voyages of Discovery
• Physiology of Calcium, Phosphate, Magnesium and Vitamin D
• Physiology of Bone
• Radiology of Osteogenesis Imperfecta, Rickets and Other Bony Fragility States
• Bone Densitometry: Current Status and Future Perspective
• A Practical Approach to Hypocalcaemia in Children
• Approach to the Child with Hypercalcaemia
• A Practical Approach to Vitamin D Deficiency and Rickets
• A Practical Clinical Approach to Paediatric Phosphate Disorders
• Primary Osteoporosis
• Osteoporosis in Children with Chronic Disease
• Genetics of Osteoporosis in Children
• A Practical Approach to Children with Recurrent Fractures
• Miscellaneous Bone Disorders
• Skeletal Aspects of Non-Accidental Injury
• Skeletal Dysplasias: An Overview
• Drugs Used in Paediatric Bone and Calcium Disorders
• Classification of Disorders of Bone and Calcium Metabolism
• Case Histories
• Appendix 1: Explanation of Abbreviations Appearing in Text
• Appendix 2: Conversion Factors between SI and ‘Conventional’ Units
• Author Index
• Subject Index