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Genetics of Human Infertility
Genetics of Human Infertility

Genetics of Human Infertility

P. H. Vogt
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pages
178 pages
language
English
format
ePUB (mobile friendly)
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Genetics of Human Infertility

P. H. Vogt
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About This Book

Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

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Information

Publisher
S. Karger
Year
2017
ISBN
9783318060980
Topic
Medicine
Subtopic
Medical Theory, Practice & Reference

Table of contents