
- English
- PDF
- Available on iOS & Android
About this book
Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research.
Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice.
This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.
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Information
Table of contents
- Cover
- Title Page
- Copyright Page
- CONTENTS
- Illustrations
- Acknowledgments
- Abbreviations
- INTRODUCTION Why Mice?
- CHAPTER ONE: Mice, Medicine, and Genetics: From Pet Rodents to Research Materials (1900โ21)
- CHAPTER TWO: Experiment and Change: Institutionalizing Inbred Mice (1922โ30)
- CHAPTER THREE: Mice for Sale: Commodifying Research Animals (1930โ33)
- CHAPTER FOUR: A New Deal for Mice: Biomedicine as Big Science (1933โ40)
- CHAPTER FIVE: RXMouse: JAX Mice in Cancer Research (1938โ55)
- CHAPTER SIX: Mouse Genetics as Public Policy: Radiation Risk in Cold War America (1946โ56)
- EPILOGUE Animals and the New Biology: Oncomouse. and Beyond
- Bibliography
- Index