Carbohydrates in Drug Design and Discovery
eBook - PDF

Carbohydrates in Drug Design and Discovery

  1. 320 pages
  2. English
  3. PDF
  4. Available on iOS & Android
eBook - PDF

Carbohydrates in Drug Design and Discovery

About this book

In recent years there has been increasing evidence of the importance of carbohydrates and glycoconjugates in biomedical applications, and the use of synthetic ligands based on carbohydrates as drugs has received much attention. Focussing on drug discovery from key targets and placing an emphasis on the multi-disciplinary approaches necessary to challenge these issues, this book comprehensively covers the new and recent discoveries in the area of carbohydrate drug discovery.

Carbohydrates in Drug Design and Discovery is split into five sections, beginning with a introduction and perspective on the current market. The book then goes on to discuss new synthetic methods in glycobiology, the use of glycobiology in chemical biology and glycobiology in drug discovery.

Providing a worldwide perspective on this broad area, and providing examples of therapeutics already developed using these methods, this book provides a comprehensive introduction, discussion and update on this fast developing field for medicinal chemists and biochemists working in industry and academia.

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Yes, you can access Carbohydrates in Drug Design and Discovery by Jesus Jimenez-Barbero, F. Javier Canada, Sonsoles Martin-Santamaria in PDF and/or ePUB format, as well as other popular books in Biological Sciences & Biochemistry. We have over one million books available in our catalogue for you to explore.

Table of contents

  1. Cover
  2. Contents
  3. Chapter 1 Carbohydrate-Protein Interactions: A 3D View by NMR
  4. Chapter 2 NMR as a Tool to Unveil the Molecular Basis of Glycan-mediated Host-Pathogen Interactions
  5. Chapter 3 Lipopolysaccharides as Microbe-associated Molecular Patterns: A Structural Perspective
  6. Chapter 4 Molecular Basis of Mycobacterium tuberculosis Recognition by the C-Type Lectin DC-SIGN: from the Modulation of Innate Immune Response to the Design of Innovative Anti-inflammatory Drugs
  7. Chapter 5 Glyconanotechnology and Disease: Gold Nanoparticles Coated with Glycosides as Multivalent Systems for Potential Applications in Diagnostics and Therapy
  8. Chapter 6 Boosting Humoral Immune Responses to Tumor-associated Carbohydrate Antigens with Virus-like Particles
  9. Chapter 7 Synthetic Glycosylated Ether Glycerolipids as Anticancer Agents
  10. Chapter 8 Carbohydrates and Glycomimetics in Alzheimer's Disease Therapeutics and Diagnosis
  11. Chapter 9 Galactofuranose Biosynthesis: Discovery, Mechanisms and Therapeutic Relevance
  12. Chapter 10 Carbohydrate-containing Matrix Metalloproteinase Inhibitors (MMPIs): A Second Childhood for Sulfonamidic Inhibitors?
  13. Chapter 11 Amphiphilic Aminoglycoside Antimicrobials in Antibacterial Discovery
  14. Chapter 12 From the Capsular Polysaccharide to a Conjugate Vaccine Containing Haemophilus influenzae Type b Synthetic Oligosaccharide
  15. Subject Index