Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project – Europe's largest public-private partnership project which aims to develop a toolbox of sustainable technologies for green chemical intermediate manufacture. Divided into two sections, the book first gives an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies. Featuring innovative research, this book is an invaluable reference for chemists across academia and industry wanting to further their knowledge and understanding of this important topic.

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Yes, you can access Green and Sustainable Medicinal Chemistry by Louise Summerton, Helen F Sneddon, Leonie C Jones, James H Clark in PDF and/or ePUB format, as well as other popular books in Physical Sciences & Environmental Science. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Royal Society of Chemistry

Year

2016

eBook ISBN

9781782625940

Edition

Topic

Physical Sciences

Subtopic

Environmental Science

Cover
Contents
Chapter 1 Green and Sustainable Chemistry: An Introduction
Chapter 2 Tools for Facilitating More Sustainable Medicinal Chemistry
Chapter 3 Renewable Solvent Selection in Medicinal Chemistry
Chapter 4 Beyond Mass-based Metrics: Evaluating the Greenness of Your Reaction
Chapter 5 The Importance of Elemental Sustainability and Critical Element Recovery for the Pharmaceutical Industry
Chapter 6 Presence, Fate and Risks of Pharmaceuticals in the Environment
Chapter 7 Benign by Design
Chapter 8 From Discovery to Manufacturing: Some SustainabilityChallenges Presented by the Requirements of Medicine Development
Chapter 9 Medicinal Chemistry: How ''Green'' is Our Synthetic Tool Box?
Chapter 10 Design of Experiments (DoE) for Greener Medicinal Chemistry
Chapter 11 Pd-catalysed Cross- couplings for the PharmaceuticalSector and a Move to Cutting-edge C–H Bond Functionalization: Is Palladium Simply Too Precious?
Chapter 12 The Growing Impact of Continuous Flow Methods on the Twelve Principles of Green Chemistry
Chapter 13 Green Catalytic Direct Amide Bond Formation
Chapter 14 Synthetic Biology for Organic Syntheses
Chapter 15 Biocatalysis for Medicinal Chemistry
Chapter 16 Base Metals in Catalysis: From Zero to Hero
Chapter 17 'Green' and Sustainable Halogenation Processes
Subject Index

About this book

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Table of contents