Supramolecular Systems in Biomedical Fields

Hans-Jorg Schneider

• Publisher: Royal Society of Chemistry
• Year: 2013
• eBook ISBN: 9781849737821
• Edition: 1
• Topic: Physical Sciences
• Subtopic: Chemistry
• Index: Chemistry

Non-covalent interactions, which are the heart of supramolecular chemistry are also the basis of most important functions of living systems. The ability to apply supramolecular chemistry principles to the life sciences, such as designing synthetic host compounds to selectively interact within biological targets, has gained wide appeal due the vast number of potential applications.

Supramolecular Systems for Biomedical Fields provides in sixteen chapters a comprehensive overview of these applications. Each chapter covers a specific topic and is written by internationally renowned experts in that area. Sensing of bioactive inorganic ions and organic substrates is the focus of several contributions, as well as interactions with proteins and nucleic acids. Specific chapters are devoted to cyclodextrins, calixarenes and cucurbiturils as most frequently used receptors, including applications such as drug delivery and protection, gene transfer and others. Other chapters address the use of combinatorial libraries, molecular imprinting techniques, enzyme assays, supramolecular gels, bioimaging, drug activation, photodynamic therapy, and antitumour metal complexes.

This timely publication will appeal to graduate students and researchers from chemical, pharmaceutical, biological, and medicinal fields interested in the supramolecular chemistry of biological systems and their practical potentials.

Table of contents

• Supramolecular Systems in Biomedical Fields
• Contents
• Chapter 1 Introduction
• Chapter 2 Signalling Techniques in Supramolecular Systems
• Chapter 3 Metal Ion Sensing for Biomedical Uses
• Chapter 4 Complexation of Biomedically Important Organic Compounds
• Chapter 5 Cyclodextrins for Pharmaceutical and Biomedical Applications
• Chapter 6 Interactions of Calix[n]arenes and Other Organic Supramolecular Systems with Proteins
• Chapter 7 Cucurbiturils in Drug Delivery And For Biomedical Applications
• Chapter 8 Nucleic Acids as Supramolecular Targets
• Chapter 9 Biomolecular Interactions of Platinum Complexes
• Chapter 10 Supramolecular Metal Complexes for Imaging and Radiotherapy
• Chapter 11 Supramolecular Gels for Pharmaceutical and Biomedical Applications
• Chapter 12 Supramolecular Enzyme Assays
• Chapter 13 Constitutional Dynamic Chemistry for Bioactive Compounds
• Chapter 14 Molecular Imprinted Polymers for Biomedical Applications
• Chapter 15 Supramolecular Approach for Tumor Imaging and Photodynamic Therapy
• Chapter 16 Designing Polymeric Binders for Pharmaceutical Applications
• Subject Index