The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle – the skin's own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and "correct" skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.

Frequently asked questions

Yes, you can cancel anytime from the Subscription tab in your account settings on the Perlego website. Your subscription will stay active until the end of your current billing period. Learn how to cancel your subscription.

No, books cannot be downloaded as external files, such as PDFs, for use outside of Perlego. However, you can download books within the Perlego app for offline reading on mobile or tablet. Learn more here.

Perlego offers two plans: Essential and Complete

Essential is ideal for learners and professionals who enjoy exploring a wide range of subjects. Access the Essential Library with 800,000+ trusted titles and best-sellers across business, personal growth, and the humanities. Includes unlimited reading time and Standard Read Aloud voice.
Complete: Perfect for advanced learners and researchers needing full, unrestricted access. Unlock 1.4M+ books across hundreds of subjects, including academic and specialized titles. The Complete Plan also includes advanced features like Premium Read Aloud and Research Assistant.

Both plans are available with monthly, semester, or annual billing cycles.

We are an online textbook subscription service, where you can get access to an entire online library for less than the price of a single book per month. With over 1 million books across 1000+ topics, we’ve got you covered! Learn more here.

Look out for the read-aloud symbol on your next book to see if you can listen to it. The read-aloud tool reads text aloud for you, highlighting the text as it is being read. You can pause it, speed it up and slow it down. Learn more here.

Yes! You can use the Perlego app on both iOS or Android devices to read anytime, anywhere — even offline. Perfect for commutes or when you’re on the go.
Please note we cannot support devices running on iOS 13 and Android 7 or earlier. Learn more about using the app.

Yes, you can access pH of the Skin: Issues and Challenges by Christian Surber,Christoph Abels,Howard Maibach,Christian, Surber,Christoph, Abels,Howard, Maibach,Howard, Maibach, P. Itin,G. B. E. Jemec,P., Itin,G.B.E., Jemec in PDF and/or ePUB format, as well as other popular books in Medicine & Immunology. We have over one million books available in our catalogue for you to explore.

Information

Publisher

Year

Print ISBN

eBook ISBN

Topic

Subtopic

201

Author 

Index

Abels, 

C.

VII, 

1,

173

Angelova-Fischer, 

I.

173

Berardesca, 

E.

33,

87

Bigliardi, 

P.L. 

108

Bíró, 

T.

54

Blaak, 

J.

132

Charruyer, 

A.

71

Choi, 

E.H. 

48

Cork, 

M.J. 

95

Dähnhardt, 

D.

166

Dähnhardt-Pfeiffer, 

S.

166

Danby, 

S.G. 

95

Darlenski, 

R.

26

Dragicevic, 

N.

183

du

Plessis, 

J.L. 

19

Farage, 

M.A. 

33

Fluhr, 

J.W. 

26

Gebert, 

A.

64,

123

Ghadially, 

R.

71

Hood, 

W.

33

Humbert, 

P.

1

Knie, 

U.

152

Kottner, 

J.

183

Maibach, 

H.

VII, 

1,

33

Neubert, 

R.H.H. 

64

Oláh, 

A.

54

Østergaard 

Knudsen, 

N.

143

Pommergaard 

Pedersen, 

G.

143

Proksch, 

E.

11

Richter, 

K.

79

Rinnerthaler, 

M.

79

Rippke, 

F.

87

Schürer, 

N.

115

Staib, 

P.

132

Stefaniak, 

A.B. 

19

Surber, 

C.

VII, 

1,

152, 

166, 

183

Szöllősi, 

A.G. 

54

Tóth, 

B.I. 

54

Weber, 

T.M. 

87

Wilhelm, 

K.-P. 

19

Wohlrab, 

J.

64,

123

Cover
Front Matter
Contents
Preface
The Acid Mantle: A Myth or an Essential Part of Skin Health?
Buffering Capacity
Measurement of Skin Surface pH
Skin Surface pH in Newborns: Origin andConsequences
Intrinsic and Extrinsic Factors Affecting Skin Surface pH
Gender, Age, and Ethnicity as FactorsThat Can Influence Skin pH
Endogenous Factors That Can Influence Skin pH
Lipids in the Skin and pH
Influence of pH on Skin Stem Cells and Their Differentiation
The Influence of Calcium on the Skin pH and Epidermal Barrier During Aging
pH and Microbial Infections
pH in Atopic Dermatitis
Role of Skin pH in Psoriasis
pH and Acne
pH and Buffer Capacity of Topical Formulations
The Relation of pH and Skin Cleansing
pH and Drug Delivery
Metamorphosis of Vehicles: Mechanisms and Opportunities
Influence of Topical Formulations: Lipid Lamella Organization and Lipid Composition of Stratum Corneum as a Surrogate Marker for Barrier Integrity
Skin Care Products: Age-Appropriate Cosmetics
Skin Care Products for Healthy and Diseased Skin
Author Index
Subject Index
Cover

About this book

Frequently asked questions

Information

Table of contents