B Cell Trophic Factors and B Cell Antagonism in Autoimmune Disease
eBook - PDF

B Cell Trophic Factors and B Cell Antagonism in Autoimmune Disease

  1. English
  2. PDF
  3. Available on iOS & Android
eBook - PDF

B Cell Trophic Factors and B Cell Antagonism in Autoimmune Disease

About this book

The understanding of B cell biology has increased and expanded enormously in the last three decades. It is now known that B cells, in addition to just differentiating into antibody-secreting cells, serve many other vital functions. For example, their roles as antigen-presenting cells and cytokine-producing cells as well as effector cells and regulatory cells are well appreciated now. Indeed, the pathologic role of B cells in many autoimmune disorders may be largely autoantibody-independent. Today, the B cell is of considerable interest not only to immunologists but also to mainstream clinicians and scientists. The current volume covers the latest information on the functions of B cells in normal and disease states, and their therapeutic antagonism. Chapters cover cutting-edge topics from the basic to the clinical, including B cells in infection and autoimmunity, CD19-CD21 signal transduction complex, marginal zone B cell physiology and disease, B cell growth and differentiation, their role in rheumatoid arthritis, SLE treatment, the BAFF/APRIL system and B lymphocyte malignancies. This book is recommended reading for cellular and molecular immunologists as well as for rheumatologists, hematologists and clinical immunologists, and all those interested in human diseases in which B cells play an important contributory role.

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Yes, you can access B Cell Trophic Factors and B Cell Antagonism in Autoimmune Disease by W. Stohl, A. N. Theofilopoulos in PDF and/or ePUB format, as well as other popular books in Medicine & Hematology. We have over one million books available in our catalogue for you to explore.

Information

Publisher
S. Karger
Year
2004
Print ISBN
9783805578516
eBook ISBN
9783318011654
Edition
1
Topic
Medicine
Subtopic
Hematology

Table of contents

  1. Contents
  2. Foreword
  3. Determinations of B Cell Fate in Immunity and Autoimmunity
  4. Regulatory Roles for Cytokine-Producing B Cells in Infection and Autoimmune Disease
  5. The CD19-CD21 Signal Transduction Complex of B Lymphocytes Regulates the Balance between Health and Autoimmune Disease: Systemic Sclerosis as a Model System
  6. Marginal Zone B Cell Physiology and Disease
  7. Dendritic Cells Control B Cell Growth and Differentiation
  8. The Biology of CD20 and Its Potential as a Target for mAb Therapy
  9. B Lymphocyte Depletion in Rheumatoid Arthritis: Targeting of CD20
  10. Treatment of SLE with Anti-CD20 Monoclonal Antibody
  11. The Biochemistry and Biology of BAFF, APRIL and Their Receptors
  12. The BAFF/APRIL System: An Important Player in Systemic Rheumatic Diseases
  13. Human B Lymphocyte Malignancies: Exploitation of BLyS and APRIL and Their Receptors
  14. BlySfulness Does Not Equal Blissfulness in Systemic Lupus Erythematosus: A Therapeutic Role for BLyS Antagonists
  15. Author Index
  16. Subject Index