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Diabetology of Pregnancy
About this book
Trends identified when estimating global prevalence suggest the world is facing a pandemic of diabetes mellitus. Consequently a rapid increase in the incidence of gestational diabetes mellitus is expected. This volume provides a comprehensive yet concise overview of the scientific and clinical characteristics of gestational diabetes as well as type 1 and type 2 diabetes mellitus during pregnancy. Throughout the book the authors adopt a multidisciplinary approach and cover aspects such as etiology, physiology, molecular biology and genetics, immunology, pathogenesis, diagnosis, treatment and management, pathology and evidence-based medicine. The role of the placenta as a fetal organ at the interface between mother and fetus is covered in depth. Basic scientists and medical researchers will find several chapters reviewing the basis of our understanding of many aspects of the disease ranging from maternal endocrinology to fuel-mediated functional teratogenesis. Obstetricians, perinatologists and health care professionals dealing with diabetes and pregnancy and the offspring of diabetic mothers will gain profound insights into current concepts in the clinical management of diabetic pregnancy including preconception diagnosis and care, and the overall perspectives when complications arise during diabetes and pregnancy as well as potential complications during diabetic pregnancy and delivery.
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Information
Table of contents
- Cover
- Contents
- Preface
- Epidemiology of Pregestational and Gestational Diabetes
- Fuel-Mediated ‘Functional Teratogenesis’ and Primary Prevention
- Endocrine Changes in Diabetic Pregnancy
- Metabolic Changes in Diabetic Pregnancy
- Leptin in the Diabetic Pregnancy
- Maternal Diabetes and Embryonic Development
- Normal and Abnormal Fetal Growth
- Effect of Nutrition on Fetal Development: A View on the Pancreatic beta-Cells
- The Human Placenta in Diabetes
- Vasculogenesis and Angiogenesis in the Diabetic Placenta
- Morphological Findings in Infants and Placentas of Diabetic Mothers
- Principles of Evidence-Based Medicine
- The Graz Approach to Diabetes in Pregnancy
- Clinical Management of Pregnancies Complicated with Type 1/Type 2 Diabetes mellitus
- Nutritional Management of Diabetes in Pregnancy
- Diabetes-Related Antibodies and Pregnancy
- Insulin and Oral Hypoglycemic Agents in Pregnancy
- Continuous Glucose Monitoring for the Evaluation and Improved Treatment Adjustment in Gravid Women with Diabetic Pregnancy
- Fetal Hypoxia and Its Monitoring in Pregestational Diabetic Pregnancies
- Ultrasonic Surveillance of the Diabetic Fetus
- Diabetic Pregnancy: Maternal Metabolic and Microvascular Complications in Type 1 Diabetes mellitus
- Pre-Eclampsia in Women with Type 1 Diabetes
- Management of Delivery
- Offspring of Diabetic Pregnancy
- Long-Term Consequences of Gestational Diabetes mellitus
- Author Index
- Subject Index