Sleep Apnea

Current Diagnosis and Treatment

W. J. Randerath, B. M. Sanner, V. K. Somers, J. J. F. Herth

• Publisher: S. Karger
• Year: 2006
• Print ISBN:
  9783805580496
• eBook ISBN:
  9783318012996
• Edition: 1
• Topic: Medicine
• Subtopic: Cardiology

In the face of the rapid developments in sleep medicine, this book seeks to present the current knowledge in the pathophysiology, clinical presentation, diagnosis, and treatment of sleep apnea. New physiological approaches to modeling sleep and recent pathophysiologic findings in upper airway mechanics as well as the importance of inflammatory and oxidative processes and the underlying genetic aspects are discussed to open up new avenues of investigation for better understanding and improved therapeutic options. Besides the well-known CPAP therapy, chapters describe novel therapeutic methods that are currently under investigation and highlight their future prospects, limitations as well as recommendations for practice. The influence of breathing disturbances on the cardiovascular system during sleep is significant. Reviews of central sleep apnea and of cardiovascular complications of sleep-disordered breathing therefore play an important role in this edition. Some of the chapters are dedicated to specific aspects in children, in the elderly and in pregnancy and receive special attention as sleep apnea is relevant to all ages. The excellent contributions to this volume will be stimulating reading to pneumologists, sleep and ENT specialists, neurologists, dental surgeons, cardiologists, obstetricians, general practitioners as well as public health specialists.

Table of contents

• Cover
• Contents
• Foreword
• Preface
• Sleep Disorders and Their Classification – An Overview
• Physiology of Sleep and Dreaming
• Physiology of Breathing during Sleep
• Physiology of the Cardiovascular, Endocrine and Renal Systems during Sleep
• History and Questionnaires
• Objectifying Sleepiness
• Portable Monitoring Systems
• Polysomnography
• Nasal, Lung and Cardiovascular Function Tests
• Upper Airway Imaging in Sleep Apnea Syndrome
• Upper Airway Obstruction in Snoring and Upper Airway Resistance Syndrome
• Obstructive Sleep Apnea-Hypopnea Syndrome: Definitions and Pathophysiology
• Oxidative Stress – The Culprit of Obstructive Sleep Apnea Syndrome
• Genetics Aspects of the Obstructive Sleep Apnea/Hypopnea Syndrome
• Upper Airway Muscles in Obstructive Respiratory Sleep Disorders
• Obstructive Sleep Apnea: Clinical Presentation, Diagnosis and Treatment
• Automatic Positive Airway Pressure Titration and Treatment
• Humidification in Sleep-Related Breathing Disorders
• Oral Appliances in the Treatment of Obstructive Sleep Apnea and Snoring
• Electrical Stimulation of the Upper Airways Muscles
• Cardiac Pacemaker Therapy in Sleep Apnea
• Surgical Treatment for Obstructive Sleep Apnea
• Alternative Therapies for Obstructive Sleep Apnea Syndrome: Behavioral and Pharmacological Options
• Central Sleep Apnea, Hypoventilation Syndromes and Periodic Breathing Disorders
• Cardiovascular Complications of Sleep-Related Breathing Disorders
• Sleep-Related Breathing Disorders in Children
• Sleep-Related Breathing Disorders in the Elderly
• Sleep-Disordered Breathing in Pregnancy
• Author Index
• Subject Index