Most indigenous microbes occur in the intestinal tract, and their interactions with the host are largely unknown. Current understanding of host-microbe interactions links early microbial contact to the origin of disease, a theory that has its roots in the hygiene hypothesis. Modern life style appears to deprive the infant of conditions that provide adequate anti-inflammatory or tolerogenic stimuli upon antigen encounter. Thus, maturational signals from the environment and the diet are insufficient to adequately shape the immune system. This publication deals with the relationship between the gut microbiota as well as altered pattern of early microbial contact and the origin of human disease. New aspects of the original hygiene hypothesis are discussed in relation to disorders spanning from allergy and autoimmunity to obesity.The results presented suggest that all these disorders may be linked to aberrant antigen absorption and immune responses associated with dysfunction of mucosal defense. Researchers, clinicians and students interested in the interaction of the host with indigenous gut bacteria and the consequences for human health will find this publication of utmost interest.
eBook - PDF
Microbial Host-Interaction: Tolerance versus Allergy
64th Nestlé Nutrition Institute Workshop, Pediatric Program, Sydney, November 2008
- 278 pages
- English
- PDF
- Available on iOS & Android
eBook - PDF
Microbial Host-Interaction: Tolerance versus Allergy
64th Nestlé Nutrition Institute Workshop, Pediatric Program, Sydney, November 2008
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Table of contents
- Cover
- Contents
- Preface
- Foreword
- Contributors
- Keynote Talks
- Development of Normal Tolerance
- Global View on Nutrition-Related Health Problems in Childhood
- Role of Allergen Exposure in Tolerance Development
- Nutrition and Immunological Homeostasis
- Summary
- Concluding Remarks
- Subject Index
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Yes, you can access Microbial Host-Interaction: Tolerance versus Allergy by P. Brandtzaeg,E. Isolauri,S. L. Prescott, Brandtzaeg, Isolauri, Prescott in PDF and/or ePUB format, as well as other popular books in Medicine & Immunology. We have over 1.5 million books available in our catalogue for you to explore.