Animal Models Of Neuropsychiatric Diseases

Michael Koch

• Publisher: ICP
• Year: 2006
• Print ISBN: 9781860946189, 9781860946189
• eBook ISBN: 9781860948022
• Topic: Medicine
• Subtopic: Neurology

Animal models of neuro- and psychopathological states in humans are an indispensable part of both experimental neurology and biological psychiatry. Written by a team of experts, this book provides an up-to-date detailed overview of the current approaches to the design of viable animal models for eight prominent neuropsychiatric diseases. The book is specifically written with the research-oriented reader in mind — both in academia and the pharmaceutical industry. It contains first-hand information on how to design viable animal models for Alzheimer's disease, epilepsy, Huntington's disease, Parkinson's disease, addiction, depression, fear and anxiety, and schizophrenia. Each chapter also critically discusses the limitations of the animal experimental approach towards an understanding of human neuropsychiatric disorders.The book is an essential source of reference for researchers who seek to successfully continue and elaborate the experimental work that will finally lead to a better understanding of the neurobiological basis of the diseases, as well as to an improvement of both diagnosis and therapy.

Table of contents

• Contents
• Contributors
• Introductory Remarks Michael Koch
• 1. Animal Models of Alzheimer’s Disease Ulrich Gartner and Thomas Arendt
• 2. Animal Models of Epilepsy Kerstin Schwabe and Ulrich Ebert
• 3. Animal Models of Huntington’s Disease Ian J. Mitchell
• 4. Animal Models of Parkinson’s Disease Werner J. Schmidt
• 5. Methods for Behavioural Assessment of Drug-Reinforcement and Addictive Features Carles Sanchis-Segura, Tarek Zghoul and Rainer Spanagel
• 6. Animal Models of Depression Paul Willner and Paul J. Mitchell
• 7. Animal Models of Fear and Anxiety Markus Fendt
• 8. Animal Models of Schizophrenia Michael Koch
• Index