Emerging Topics In Physical Virology

Peter G Stockley, Reidun Twarock

• Publisher: ICP
• Year: 2010
• Print ISBN:
  9781848164642
  9781848164642
• eBook ISBN:
  9781848164666
• Topic: Biological Sciences
• Subtopic: Biophysics
• Index: Biological Sciences

Emerging Topics in Physical Virology is a state-of-the-art account of recent advances in the experimental analysis and modeling of structure, function and dynamics of viruses. It is the first interdisciplinary book that integrates a review of relevant experimental techniques, such as cryo-electron microscopy, atomic force microscopy and mass spectrometry with the latest results on the biophysical and mathematical modeling of viruses. The book comprehensively covers the structure and physical properties of the protein envelopes that encapsulate and hence protect the delicate viral genome, their assembly and disassembly, the organization of the viral genome, infection, evolution, as well as applications of viruses in Biomedical Nanotechnology. It is an essential primer for scientists working in all aspects of virology, including the increasing use of viruses and virus-like particles in bio- and nano-technology. Its review style makes it moreover suitable for non-experts as an introduction into this exciting research area.

Table of contents

• Contents
• Contributors
• Preface
• Chapter 1: Cryo-Electron Microscopy of Viruses Neil A. Ranson and Peter G. Stockley
• Chapter 2: What Does it Take to Make a Virus: The Concept of the Viral ‘Self’ Nicola G. A. Abrescia, Jonathan M. Grimes, Elizabeth E. Fry, Janne J. Ravantti, Dennis H. Bamford and David. I. Stuart
• Chapter 3: Beyond Quasi-Equivalence: New Insights Into Viral Architecture via Affine Extended Symmetry Groups Thomas Keef and Reidun Twarock
• Chapter 4: Mechanical Properties of Viruses Wouter H. Roos and Gijs J. L. Wuite
• Chapter 5: Investigating Viral Structure, Function and Dynamics with Mass Spectrometry Eric B. Monroe and Peter E. Prevelige
• Chapter 6: An Overview of Capsid Assembly Kinetics J. Zachary Porterfield and Adam Zlotnick
• Chapter 7: Assembly and Disassembly of Deltahedral Viral Shells Alexander Yu. Morozov, Joseph Rudnick, Robijn F. Bruinsma and William S. Klug
• Chapter 8: What Determines the Size of an RNA Virus? Charles M. Knobler and William M. Gelbart
• Chapter 9: Physics of Viral Infectivity: Matching Genome Length with Capsid Size Alex Evilevitch and Martin Castelnovo
• Chapter 10: Topology of Viral DNA Javier Arsuaga, Joaquim Roca and De Witt Sumners
• Chapter 11: The Use of Viruses in Biomedical Nanotechnology Kristopher J. Koudelka and Marianne Manchester
• Index