Science of Synthesis: Catalytic Reduction in Organic Synthesis Vol. 2

Johannes G. de Vries

• Publisher: Thieme
• Year: 2018
• Print ISBN:
  9783132406261
• eBook ISBN:
  9783132406292
• Edition: 1
• Topic: Physical Sciences
• Subtopic: Organic Chemistry

Catalytic reductions are among the most used synthetic transformations, and the past 15 years have seen great progress in this field. Science of Synthesis: Catalytic Reduction in Organic Synthesis includes the latest developments, as well as selective coverage of more well-established methods. Both heterogeneous and homogeneous catalytic systems are covered, and enantioselective methodology is well represented. There is a focus on the use of metal nanoparticles, both in suspension as well as on solid supports. Furthermore, the advent of research on the conversion of renewable resources into fuels and chemicals has given a great impetus to the field, as deoxygenations are often the first step in the conversion of biomass and this can often be achieved using hydrogenation or hydrogenolysis reactions. Scope, limitations, and mechanism of the reactions are discussed and key experimental procedures are included.

Table of contents

• Science of Synthesis: Catalytic Reduction in Organic Synthesis 2
• Title Page
• Copyright
• Preface
• Science of Synthesis Reference Library
• Abstracts
• Overview
• Table of Contents
• Introduction
• 2.1 Reduction of Aldehydes
• 2.2 Transfer Hydrogenation of Ketones to Alcohols
• 2.3 Catalytic Hydrogenation of Ketones
• 2.4 Hydrogenolysis of Aryl Ketones and Aldehydes, Benzylic Alcohols and Amines, and Their Derivatives
• 2.5 Reduction of Carboxylic Acids and Derivatives to Aldehydes and Alcohols
• 2.5.1 Homogeneous Catalytic Hydrogenation of Carboxylic Acids, Anhydrides, Esters, Amides, and Acid Chlorides
• 2.5.2 Heterogeneous Catalytic Hydrogenation of Carboxylic Acids, Anhydrides, Esters, Amino Acids, and Amides
• 2.6 Reduction of Imines and Reductive Amination of Aldehydes and Ketones
• 2.7 Reduction of Nitro Compounds to Amines, Azo Compounds, Hydroxylamines, and Oximes, and Reduction of N-Oxides to Amines
• 2.8 Reduction of Azides
• 2.9 Catalytic Reduction of Nitriles
• Keyword Index
• Author Index
• Abbreviations
• Back Cover