Applications of Domino Transformations in Organic Synthesis, Volume 1

Prof. Scott A. Snyder

• Publisher: Thieme
• Year: 2015
• Print ISBN: 9783131731418
• eBook ISBN: 9783132028517
• Edition: 1
• Topic: Physical Sciences
• Subtopic: Chemistry
• Index: Chemistry

The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals.

"Science of Synthesis: Applications of Domino Transformations in Organic Synthesis" explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others.

Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.

Table of contents

• Science of Synthesis Applications of Domino Transformations in Organic Synthesis 1
• Title Page
• Copyright
• Preface
• Science of Synthesis Reference Library
• Volume Editor's Preface
• Abstracts
• Applications of Domino Transformations in Organic Synthesis 1
• Table of Contents
• Introduction
• 1.1 Polyene Cyclizations
• 1.2 Cation–π Cyclizations of Epoxides and Polyepoxides
• 1.3 Metathesis Reactions
• 1.4 Radical Reactions
• 1.5 Non-Radical Skeletal Rearrangements
• 1.6 Metal-Mediated Reactions
• Keyword Index
• Author Index
• Abbreviations