Antibiotics Manual
eBook - ePub

Antibiotics Manual

A Guide to commonly used antimicrobials

  1. English
  2. ePUB (mobile friendly)
  3. Available on iOS & Android
eBook - ePub

Antibiotics Manual

A Guide to commonly used antimicrobials

About this book

A comprehensive compendium of all commonly used antibiotics, including indications, side effects, dosage information, and drug/food interactions

Antibiotics Manual: A Guide to Commonly Used Antimicrobials, Second Edition is a unique, user-friendly guide made for all who prescribe antibiotics. It's the only book available that takes a 100% drug-listed approach to 200 of the most common antibiotics prescribed to patients each day. Presented in full color, it's also a convenient reference for every clinician to consult once the decision to use a particular antibiotic has been reached.

This edition of Antibiotics Manual includes newer antibiotics that have been released since the publication of the First Edition and updates prescribing information for the older antibiotics. This all-new Second Edition:

  • Has a color-coded interior design which provides quick and easy point of care access for the user
  • Includes 200 of the most commonly prescribed antibiotics, listed by both brand and generic names
  • Features important recently-released antibiotics such as ceftaroline, tedizolid, and bedaquiline

Antibiotics Manual: A Guide to Commonly Used Antimicrobials, Second Edition is a welcome book for physicians in all specialties of medicine who prescribe antibiotics. It is also a handy tool for pharmacists, nurses, nurse practitioners, and physician assistants who want more information on the drugs they administer.

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Information

Publisher
Wiley-Blackwell
Year
2017
Print ISBN
9781119220756
eBook ISBN
9781119220763
Edition
2
Topic
Medicine
Subtopic
Pharmacology

INFERGEN (Interferon Alpha) Infergen (Interferon Alfacon‐1) Injection Intron A (Interferon Alfa‐2a) Injection

Check-list icon.
BASIC CHARACTERISTICS

Class: Alpha interferon.
Mechanism of Action: After binding to the cell‐surface receptor, production of several interferon‐stimulated gene products lead to antiviral, antiproliferative, and immunomodulatory effects, regulation of cell surface major histocompatibility antigen (HLA class I and class II) expression, and regulation of cytokine expression.
Mechanism of Resistance: Unknown.
Metabolic Route: Interferon is metabolized into amino acids.

FDA (Food and Drugs Authority) logo.
FDA‐APPROVED INDICATIONS

Both Infergen and Intron A are indicated for treatment of chronic hepatitis C in patients 18 years and older.
Intron A is also indicated for the treatment of hepatitis B.
Intron A is also indicated for hairy cell leukemia, malignant melanoma, follicular lymphoma, condylomata acuminata, and AIDS‐related Kaposi sarcoma.
Other uses: Hepatitis B.

Icon of an atom molecule.
SIDE EFFECTS/TOXICITY

WARNING: Alpha interferons cause or aggravate fatal or life‐threatening neuropsychiatric, autoimmune, ischemic, and infectious disorders. Patients should be monitored closely with periodic clinical and laboratory evaluations. Patients with persistently severe or worsening signs or symptoms of these conditions should be withdrawn from therapy. In many but not all cases these disorders resolve after stopping alpha interferon therapy.
Interferon is contraindicated in patients with known hypersensitivity to alpha interferons or to any component of the product, decompensated hepatic disease, or autoimmune hepatitis.
Other adverse events:
General: fever, hypersensitivity.
Neuropsychiatric disorders: depression, suicide, psychosis, aggressive behavior, nervousness, anxiety, emotional lability, abnormal thinking, agitation, apathy, and relapse of drug addiction.
Infections
Bone marrow suppression
Cardiovascular disorders, including hypertension, tachycardia, palpitation, tachyarrhythmias, supraventricular arrhythmias, chest pain, and myocardial infarction.
Hypersensitivity
Endocrine disorders: hyperthyroidism, hypothyroidism, hyperglycemia, diabetes mellitus, elevated serum triglycerides.
Autoimmune disorders: autoimmune thrombocytopenia, idiopathic thrombocytopenic purpura, psoriasis, SLE, thyroiditis, and rheumatoid arthritis.
Pulmonary: pneumonia and interstitial pneumonitis.
Gastrointestinal disorders: hemorrhagic/ischemic, ulcerative colitis, pancreatitis, and hepatic decompensation.
Ophthalmologic disorders: decrease or loss of vision, macular edema, retinal artery or vein thrombosis, retinal hemorrhages, cotton wool spots, optic neuritis, and papilledema.
Cerebrovascular disorders: ischemic and hemorrhagic cerebrovascular events.

Conical flask icon.
DRUG INTERACTIONS/FOOD INTERACTIONS

None.

Icon of two capsules.
DOSING

Chronic hepatitis C
Infergen (interferon alfacon‐1): nine mcg three times weekly administered subcutaneously as a single injection for 24 weeks. At least 48 hours should elapse between doses.
Patients who did not respond or relapsed following its discontinuation may be subsequently treated with 15 mcg times a week (tiw) administered SC as a single injection for up to 48 weeks.
Dose reduction to 7.5 mcg may be necessary following an intolerable adverse event.
Intron A: 3 MIU three times a week (tiw) administered subcutaneously or intramuscularly for 18–24 months in patients who tolerate therapy and normalize ALT at 16 weeks of treatment. If severe adverse reactions develop during Intron A treatment, the dose should be modified (50 % reduction) or therapy should be temporarily discontinued until the adverse reactions abate.
Chronic hepatitis B
Intron A: 30 to 35 million IU per week, administered subcutaneously or intramuscularly, either as 5 million IU daily (q d) or as 10 million IU three times a week (tiw) for 16 weeks.

Global icon.
SPECIAL POPULATIONS

RENAL IMPAIRMENT: Interferon should be used with caution in patients with renal insufficiency.
HEPATIC DYSFUNCTION: Interferon should not be administere...

Table of contents

  1. COVER
  2. TITLE PAGE
  3. TABLE OF CONTENTS
  4. PREFACE
  5. ABELCET (Amphotericin B Lipid Complex)
  6. ALBENZA (Albendazole)
  7. ALINIA (Nitazoxanide)
  8. AMBISOME (Liposomal Amphotericin B)
  9. AMIKIN (Amikacin)
  10. AMOXICILLIN
  11. AMPHOTEC (Amphotericin B Colloidal Dispersion – ABCD)
  12. AMPICILLIN
  13. ANCEF (Cefazolin)
  14. ANCOBON (Flucytosine)
  15. ANTIMINTH (Pyrantel Pamoate)
  16. ARALEN (Chloroquine Phosphate and Hydroxychloroquine)
  17. ARTESUNATE
  18. ATABRINE (Quinacrine HCl)
  19. ATRIPLA (Tenofovir/Emtricitabine/Efavirenz)
  20. AUGMENTIN, AUGMENTIN 600ES, AUGMENTIN XR (Amoxicillin-Clavulanate Potassium)
  21. AVELOX (Moxifloxacin)
  22. AVYCAZ (Ceftazidime and Avibactam Sodium Powder)
  23. AZACTAM (Aztreonam)
  24. BACTRIM, BACTRIM DS, SEPTRA, SEPTRA DS (Trimethoprim/Sulfamethoxazole)
  25. BARACLUDE (Entecavir)
  26. BENZATHINE PENICILLIN, PENICILLIN G, PENICILLIN V, PROCAINE PENICILLIN (Penicillin)
  27. BENZNIDAZOLE
  28. BIAXIN (Clarithromycin)
  29. BILTRICIDE (Praziquantel)
  30. BITIN (Bithionol)
  31. BROACT, CEFROM KEITEN, CEFIR (Cefpirome)
  32. CANCIDAS (Caspofungin)
  33. CAPASTAT (Capreomycin)
  34. CEDAX (Ceftibuten)
  35. CEFACLOR
  36. CEFIZOX (Ceftizoxime)
  37. CEFOTAN (Cefotetan)
  38. CEFTIN (Cefuroxime Axetil), ZINACEF (Cefuroxime)
  39. CEFZIL (Cefprozil)
  40. CHLOROMYCETIN (Chloramphenicol)
  41. CHLOROQUINE PHOSPHATE (Aralen), HYDROXYCHLOROQUINE
  42. CIPRO (Ciprofloxacin), CIPRO XR
  43. CLAFORAN (Cefotaxime)
  44. CLEOCIN (Clindamycin)
  45. COARTEM (Artemether/Lumefantrine)
  46. COLY-MYCINÂŽ M PARENTERAL (Colistimethate for Injection)
  47. COLY-MYCIN (Colistimethate Sodium)
  48. COMBIVIR (Zidovudine plus Lamivudine)
  49. COMPLERA (Tenofovir + Emtricitabine + Rilpivirine)
  50. COPEGUS, REBETOL, RIBASPHERE (Ribavirin Oral)
  51. CRESEMBA (Isavuconazole)
  52. CUBICIN (Daptomycin)
  53. CYTOVENE (Ganciclovir Capsules and IV)
  54. DAKLINZA (Daclatasvir)
  55. DALVANCE (Dalbavancin)
  56. DAPSONE
  57. DARAPRIM (Pyrimethamine)
  58. DELTYBA (Delamanid)
  59. DESCOVY (Tenofovir Alafenamide + Emtricitabine)
  60. DICLOXACILLIN
  61. DIFICID (Fidaxomicin)
  62. DIFLUCAN (Fluconazole)
  63. DORIBAX (Doripenem)
  64. DORYX (Doxycycline Delayed Release), VIBRAMYCIN (Doxycycline)
  65. DURICEF (Cefadroxil)
  66. DYNACIN (Minocycline Tablets), MINOCIN (Minocycline Capsules)
  67. EDURANT (Rilpivirine)
  68. Emtriva (Emtricitabine)
  69. EPCLUSA (Sofosbuvir + Velpatasvir)
  70. EPIVIR (Lamivudine)
  71. EPZICOM (Lamivudine plus Abacavir)
  72. ERAXIS (Anidulafungin)
  73. ERYTHROMYCIN
  74. EVOTAZ (Atazanavir + Cobicistat)
  75. FACTIVE (Gemifloxacin)
  76. FAMVIR (Famciclovir)
  77. FLAGYL (Metronidazole)
  78. FLOXIN (Ofloxacin)
  79. FORTAZ (Ceftazidime), TAZICEF
  80. FOSCAVIR (Foscarnet)
  81. FUNGIZONE (Amphotericin B)
  82. FURADANTIN, MACROBID, MACRODANTIN (Nitrofurantoin)
  83. FUZEON (Enfuvirtide)
  84. GARAMYCIN (Gentamicin)
  85. GENVOYA (Tenofovir Alafenamide + Emtricitabine + Elvitegravir + Cobicistat)
  86. GERMANIN (Suramin sodium)
  87. GLUCANTIME (Meglumine Antimonite)
  88. GRIFULVIN V, GRIS-PEG (Griseofulvin)
  89. HARVONI (Ledipasvir + Sofosbuvir)
  90. HEPSERA (Adefovir)
  91. HETRAZAN (Diethyl Carbamazine/DEC)
  92. IMPAVIDO (Miltefosine)
  93. INFERGEN (Interferon Alpha) Infergen (Interferon Alfacon-1) Injection Intron A (Interferon Alfa-2a) Injection
  94. INTELENCE (Etravirine)
  95. INTRON A (Interferon Alpha) Infergen (Interferon Alfacon-1) Injection Intron A (Interferon Alfa-2a) Injection
  96. INVANZ (Ertapenem)
  97. ISENTRESS (Raltegravir)
  98. ISONIAZID
  99. KALETRA (Lopinavir/Ritonavir)
  100. KANTREX (Kanamycin)
  101. KEFLEX (Cephalexin)
  102. KETOCONAZOLE
  103. LAMISIL (Terbinafine)
  104. LAMPIT (Nifurtimox)
  105. LAMPRENE (Clofazimine)
  106. Lariam (Mefloquine Hydrochloride)
  107. LEVAQUIN (Levofloxacin)
  108. LEXIVA (Fosamprenavir)
  109. MALARONE (Atovaquone/Proguanil)
  110. MANDOL (Cefamandole)
  111. MAXIPIME (Cefepime)
  112. MEFOXIN (Cefoxitin)
  113. MEL-B (Melarsoprol B)
  114. MEPRON (Atovaquone)
  115. MERREM (Meropenem)
  116. MINTEZOLE (Thiabendazole)
  117. MONUROL (Fosfomycin)
  118. MYAMBUTOL (Ethambutol Hydrochloride)
  119. MYCAMINE (Micafungin)
  120. MYCOBUTIN (Rifabutin)
  121. NAFCILLIN
  122. NEBUPENT, PENTAM (Pentamidine)
  123. NEO-FRADIN, NEOMYCIN (Neomycin)
  124. NORVIR (Ritonavir)
  125. NOXAFIL (Posaconazole)
  126. ODEFSEY (Tenofovir alafenamide + Emtricitabine + Rilpivirine)
  127. OLYSIO (Simeprevir)
  128. OMNICEF (Cefdinir)
  129. ORBACTIVE (Oritavancin)
  130. ORNIDYL (Eflornithine)
  131. OXACILLIN
  132. PASER (Para-aminosalicylate Sodium)
  133. PEGASYS (Peginterferon alpha-2a)
  134. PEGINTRON (Peginterferon alpha-2b)
  135. PENTOSTAM (Stibogluconate)
  136. PIPRACIL (Piperacillin)
  137. POLYMYXIN B INJECTION (Polymyxin B Sulfate)
  138. PREZCOBIX (Darunavir + Cobicistat)
  139. PREZISTA (Darunavir)
  140. PRIFTIN (Rifapentine)
  141. PRIMAQUINE (Primaquine Phosphate)
  142. PRIMAXIN (Imipenem-Cilastatin Sodium)
  143. PROLOPRIM (Trimethoprim)
  144. PYRAZINAMIDE
  145. QUINIDINE
  146. QUININE
  147. RAPIVAB (Peramivir)
  148. RELENZA (Zanamivir)
  149. RETROVIR (Zidovudine)
  150. REYATAZ (Atazanavir)
  151. RIFADIN, RIFADIN IV (Rifampin)
  152. RIFAMATE (Rifampin + Isoniazid)
  153. RIFATER (Rifampin + Isoniazid + Pyrazinamide)
  154. ROCEPHIN (Ceftriaxone)
  155. ROVAMYCINE (Spiramycin)
  156. SELZENTRY (Maraviroc)
  157. SEROMYCIN (Cycloserine)
  158. SIRTURO (Bedaquiline)
  159. SIVEXTRO (Tedizolid)
  160. SOVALDI (Sofosbuvir)
  161. SPECTRACEF (Cefditoren pivoxil)
  162. SPORANOX (Itraconazole) (capsules and solution)
  163. STREPTOMYCIN
  164. STRIBILD (Tenofovir + Emtricitabine + Elvitegravir + Cobicistat)
  165. STROMECTOL (Ivermectin)
  166. SULFADIAZINE
  167. SUPRAX (Cefixime)
  168. SUSTIVA (Efavirenz)
  169. TAMIFLU (Oseltamivir)
  170. TECHNIVIE (Ombitasvir + Paritaprevir + Ritonavir)
  171. TEFLARO (Ceftaroline Fosamil)
  172. TETRACYCLINE HYDROCHLORIDE
  173. TIGACYL (Tigecycline)
  174. TIMENTIN (Ticarcillin Disodium–Clavulanate Potassium)
  175. TINDAMAX (Tinidazole)
  176. TIVICAY (Dolutegravir)
  177. TOBRAMYCIN
  178. TRECATOR (Ethionamide)
  179. TRIUMEQ (Abacavir + Lamivudine + Dolutegravir)
  180. TRIZIVIR (Zidovudine, Lamivudine, and Abacavir)
  181. TROBICIN (Spectinomycin)
  182. TRUVADA (Tenofovir and Emtricitabine)
  183. TYBOST (Cobicistat)
  184. TYZEKA (Telbivudine)
  185. UNASYN (Ampicillin Sodium–Sulbactam Sodium)
  186. VALCYTE (Valganciclovir)
  187. VALTREX (Valacyclovir)
  188. VANCOCIN (Vancomycin-PO)
  189. VANCOMYCIN-(Intravenous Only)
  190. VANSIL (Oxamniquine)
  191. VANTIN (Cefpodoxime)
  192. VEMLIDY (Tenofovir Alafenamide Fumarate (TAF))
  193. VFEND (Voriconazole)
  194. VIBATIV (Telavancin)
  195. VIEKIRA PAK (Dasabuvir + Ombitasvir + Paritaprevir + Ritonavir)
  196. VIRAMUNE (Nevirapine)
  197. VIRAZOLE (Ribavirin Inhaled)
  198. VIREAD (Tenofovir Disoproxil Fumarate)
  199. VISTIDE (Cidofovir)
  200. VITEKTA (Elvitegravir)
  201. XIFAXAN (Rifaximin)
  202. YODOXIN (Iodoquinol)
  203. YOMESAN (Niclosamide)
  204. ZEPATIER (Elbasvir and Grazoprevir)
  205. ZERBAXA (Ceftolozane and Tazobactam)
  206. ZIAGEN (ABACAVIR)
  207. ZITHROMAX, ZMAX (Azithromycin)
  208. ZOSYN (Piperacillin–Tazobactam)
  209. ZOVIRAX (Acyclovir)
  210. ZYVOX (Linezolid)
  211. HELPFUL FORMULAS, EQUATIONS, AND DEFINITIONS
  212. SELECTED ANTIMICROBIAL TOXICITIES
  213. SELECTED ANTIMICROBIAL COVERAGE
  214. BIBLIOGRAPHY AND REFERENCES
  215. END USER LICENSE AGREEMENT

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