Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results.
Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animal studies for improving human therapy and gives recommendations for future drug development.
eBook - ePub
Animal Models for Human Cancer
Discovery and Development of Novel Therapeutics
- English
- ePUB (mobile friendly)
- Available on iOS & Android
eBook - ePub
Animal Models for Human Cancer
Discovery and Development of Novel Therapeutics
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Table of contents
- Cover
- Previous Volumes of this Series
- Title Page
- Copyright
- Table of Contents
- List of Contributors
- Preface
- A Personal Foreword
- Chapter 1: Introduction
- Chapter 2: Ethical Aspects of the Use of Animals in Translational Research
- Chapter 3: Study Design
- Chapter 4: Improving External Validity of Experimental Animal Data
- Chapter 5: How to End Selective Reporting in Animal Research
- Chapter 6: A Comprehensive Overview of Mouse Models in Oncology
- Chapter 7: Mouse Models of Advanced Spontaneous Metastasis for Experimental Therapeutics
- Chapter 8: Spontaneous Animal Tumor Models
- Chapter 9: Dog Models of Naturally Occurring Cancer
- Chapter 10: Improving Preclinical Cancer Models: Lessons from Human and Canine Clinical Trials of Metronomic Chemotherapy
- Index
- End User License Agreement
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Yes, you can access Animal Models for Human Cancer by Marianne I. Martic-Kehl,Pius August Schubiger, Raimund Mannhold,Hugo Kubinyi,Gerd Folkers in PDF and/or ePUB format, as well as other popular books in Medicine & Pharmacology. We have over 1.5 million books available in our catalogue for you to explore.