ABC of Autism provides clinicians and medical students with a succinct, evidence-based overview of the symptoms, evaluation, treatment, and management of autism in both daily practice and for ongoing patient support plans. This accessible and informative guide allows primary healthcare professionals to quickly reference the essential information required for appropriate patient care.
Compact yet comprehensive, this book offers concise and focused chapters covering topics ranging from basic epidemiology and key diagnostic features to managing behavioural difficulties and co-morbidities, such as ADHD and dyspraxia. Full-colour illustrations reinforce understanding of the condition while actual case studies demonstrate contemporary practices and real-life scenarios.
ABC of Autism is a valuable resource for GPs, paediatricians, speech therapists, educational psychologists, medical and nursing students, and practitioners responsible for coordinating multidisciplinary care for patients with autism.
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Autism is a relatively common neurodevelopmental condition with a prevalence of over 1% in many populations.
Autism is defined by the presence of social communication and social interaction difficulties and restricted, repetitive patterns of behaviour, interests and activities which can vary in severity.
Autism has a heterogeneous clinical presentation because of variations in the core features and the presence or absence of associated conditions.
The diagnosis of autism is a clinical diagnosis.
There is no cure for autism but early intervention can have a significant impact upon overall wellâbeing.
Definition
Autism spectrum disorder (or autism) is a relatively common neurodevelopmental condition with a heterogeneous underlying basis which is incompletely understood. The definition of autism is based on the presence of impairments in social communication and social interaction and restricted, repetitive patterns of behaviour, interests or activities (Figure 1.1). These impairments vary greatly in severity, and whilst often noticeable during childhood can go undetected until later in life.
The neurodiversity movement has had a large impact on the terms of discourse when referring to autism and, for many people, use of the term âautism spectrum conditionâ is preferred to the use of the term â⌠disorderâ, whilst plural terminology (e.g. âdisordersâ) is also often used to highlight the heterogeneous nature of the condition. The terms âautism,â âautism spectrum disorder(s)â and, occasionally, âautism spectrum conditionâ, are therefore used interchangeably in this book. (However, for diagnostic purposes, in a clinical setting, it remains sensible to use conventional terminology in a consistent way to avoid confusion.)
History
The term âautismâ is derived from the Greek word âautos,â meaning âself,â and was first used in 1910 by Eugen Bleuler (Figure 1.2) in relation to schizophrenia, to describe the withdrawal of schizophrenic patients into their own fantasies. However, the earliest clinically based descriptions of what we would now recognise to be autistic patients were not written until many years later (although there is considerable interest amongst researchers in older historical descriptions of individuals who seem to possess autistic traits). The first wellâdescribed clinical account was written by Sukhareva in 1926 although credit for the first detailed descriptions of autism are usually attributed to Leo Kanner in 1943 and then to Hans Asperger in 1944. Opinion is divided over who âgot there firstâ, and who knew what about the otherâs work â a controversial area which lies outside the scope of this book. Aspergerâs seminal contribution to the field fell into neglect in the years around the Second World War before being rehabilitated in 1981 by Lorna Wing who coined the eponymous term âAspergerâs syndromeâ.
Epidemiology
The reported prevalence of autism has increased in recent decades, with estimates of over 1% being made in some largeâscale surveys. It is not yet clear how much of this increase could be caused by an actual increased incidence or whether it is just that the change is the result of better public awareness, improved recognition by professionals and a widening of the diagnostic criteria.
Largeâscale studies have shown that autism affects 2â3 times more males than females. This could be because of underârecognition in females or because of a genuine sex difference.
Aetiology
Controversy over aetiology has dogged the condition from early on. It was seen â erroneously â by some as an acquired condition resulting from parentâchild interactions, with âblameâ in some quarters attached to ârefrigerator mumsâ â a theory that was popularised in the 1950s by Bruno Bettelheim. The 1960s saw a shift from ânurtureâbasedâ explanatory models towards ânatureâbasedâ models and towards undertaking research to address the biological basis for the disease. This biological basis remains incompletely understood. What is clear is that there is a strong genetic basis for autism, along with a clear role for environmental risk factors. It has been known for some time that a sibling of an affected individual is more likely to have autism than a general member of the population: 10% in comparison to 1%. Furthermore, the risk of a monozygotic twin having autism is greater than the risk in a dizygotic twin. More recent research has identified that there are multiple candidate genetic mutations, many of which are uncommon or rare, whose interactions may have a role in how the autistic phenotype is expressed. It is thought that the nonâgenetic risk factors that have been identified may interact with genetic factors and thus affect how a phenotype is expressed in an individual. Some of this work has not been without controversy, most notably the wellâpublicised scare over a study (published and subsequently retracted by The Lancet) that erroneously showed an association between the mumps, measles and rubella (MMR) vaccine and autism and which led to a significant decline in immunisation rates in the UK in the early 21st century.
Clinical features
Whilst the origin of the term âautismâ suggests a personâs withdrawal into themselves, the idea that everyone with autism is highly withdrawn and isolated is incorrect and only describes a proportion of individuals with the condition. The term âspectrumâ is used to denote the heterogeneity that is seen in the clinical features of different individuals with the condition. In addition, the autistic phenotype is often expressed differently within the same individual as they move from childhood to adolescence and adulthood.
As well as the core features, those with autism can present with coâmorbid or associated conditions: mood disorders, anxiety disorders, attention deficit hyperactivity disorder (ADHD), learning disability, dyspraxia and epilepsy.
Diagnosis
The diagnosis of autism can theoretically be made at any age, although it would take confidence to make a diagnosis in a child below the age of 2â3 years. The mean age of diagnosis in the UK is currently about 5 years although a diagnosis can occur several decades after this. Such a late diagnosis occurs in many conte...