The Control of Tumour Growth and its Biological Bases

W. Davis, C. Maltoni, St. Tanneberger, W. Davis, C. Maltoni, St. Tanneberger

• Verlag: De Gruyter
• Jahr: 2022
• ISBN drucken: 9783112611371
• eBook-ISBN: 9783112611388
• Auflage: 1

Inhaltsverzeichnis

• Contents
• Introduction
• Invasion and Metastasis as Targets for Tumour Therapy
• Primary Invasion: Natural Inhibitors
• Effect of Desacetyl Vinblastine Amide Sulphate or Vindesine (VDS) against the In Vivo Invasion and Formation of Tumour Metastasis
• Invasion and Metastases as Targets for Tumour Therapy. An Overview
• Invasiveness of Brain Tumour Cells In Vivo and In Vitro
• Anti-inyasiveness of Microtubule Inhibitors is due to Interference with the Cytoplasmic Microtubule Complex
• Metastasis: Mitostatic Drugs
• Anticoagulant Treatment of Cancer
• Reactivity of a Monoclonal Antibody (B72.3) with Fixed Sections of Human Mammary Carcinomas
• Polyamine Oxidation in Relation to Tumour Growth and Metastasis
• Partial Purification of an Epidermal Growth Inhibitor (Chalone)
• Hormone. Receptors
• Estradiol Receptor in Human Breast Cancers and Prognosis
• External Quality Assessment Scheme of Estradiol Receptor Assay: An Italian Survey
• Methodological and Clinical Studies of the Steroid Receptor Assay in Primary Breast Cancer
• The Value of Hormone Receptor Assays for Prediction of the Effectiveness of Endocrine Therapy in Breast Cancer
• The Cancer Cell Surface as a Target for Tumour Therapy
• Normal and Pathological Cell Communication
• The Cells Surface as Target for Alkylating Agents
• The Synergistic Effect of Drugs and Antibodies
• Cancerostatic Lectins
• Ribosome-inactivating Proteina as Possible Chemotherapeutic Agents
• Selective Targeting of Ricin A Chain to a Murine B Cell Tumour by Anti-Immunoglobulin Antibodies
• Development of New Drugs
• The Generation of Reactive Molecular Species during the Oxidation of 9-Hydroxyellipticine Derivatives. Interest of Prooxidant Compounds in the Design of Anti-Cancer Drugs.
• Development of Nitroimidazoles
• Development of New Drugs — Immunomodulating Agents
• Development of Potential Clinical Alternatives to Hexamethylmelamine
• Synergistic Interaction of an Alkylating Agent (Lycurim) and an Antimetabolite (Pyrazofurin) on Heptoma 3924A Cells in Culture
• Phase II Evaluation of 4-Thiazolidine-Carboxylic Acid (Thioproline) in Advanced Epidermoid Head and Neck Tumours
• The Effect of a Bifunctional N-Notrosoureido Derivative (GYKI-13324) on Experimental Metastasis Models
• Long-term Toxic and Carcinogenic Effects of Cytostatic Drugs
• VP 16-213 (Etoposide; NSC-141540; Vepesid): A Review
• New Platinum Anti-Cancer Drugs
• The Status of Proteolytic Enzymes in Oncology
• Marcellomycin: A New Class II Anthracycline
• Biological Response Modifiers
• Interferon
• Comparative Interferon-Inducing and Anti-Tumour Activity of Substituted Pyrimidinones
• Influence of Human Leucocyte Interferon on Squamous-Cell Carcinoma of Uterine Cervix: Clinical, Histological and Histochemical Observations
• Effect of Interferon on Malignant Head and Neck Tumours
• Polyamines and Neoplasia: A Review of Present Knowledge of Their Function and Therapeutic Potential
• Retinoids
• The Role of Drug-Induced Differentiation in the Control of Tumour Growth
• Modifying Effect of the Sex Hormonal Environment on the Growth of Basophilic Foci and Hepatocellular Carcinoma
• Phase II Clinical Trial of cis-Dichlorodiammine Platinum (cis-DDP) in Metastatic Brain Tumours — a Preliminary Report
• Adriamycin: Experimental Evidence of Carcinogenicity
• Electroreduction, Mutagenicity and Antimicrobial Activity of 5-Nitroimidazole Derivatives
• Mechanism of the Antileukemic Action of DTIC and its Benzenoid Analog DM-COOK in mice
• Laboratory Assessment of Therapeutic Activity
• The Role of In Vitro Techniques in Assessing Antineoplastic Therapeutic Activities
• In Vivo Tests — Xenografts
• Suitable Models for Long-Term Bioassays on the Therapeutic and Toxic effects of Antiblastic Drugs: Liver Angiosarcomas Produced in Sprague-Dawley Rats by Vinyl Chloride
• Role of some Biological Parameters in Drug Sensitivity and Resistance of Tumour Cells
• Analysis of Cytotoxic and Cytostatic Effects
• An Appraisal of Current In Vivo and In Vitro Screening Methods
• Clinical Relevance of some Useful Methods for In-Vitro Testing of Cytostatic Sensitivity in Cases of Ovarian Cancers
• Immunoglobulin Producing Cell Infiltration in Colorectal Cancer Tissues Correlated with Patients Survival
• Suitable Models for Long-Term Bioassays of Therapeutic and Toxic Effects of Antiblastic Drugs: Brain Tumours of Neuronal Cells and Primitive Bipotential Precursors Produced in Sprague-Dawley Rats by Vinyl Chloride
• Laboratory Assessment of Therapeutic Activity (with Particular Regard to Chemotherapy): Relevant Animal Models
• Biological Significance and Dose-Dependent Effect of 'Resistocell' on Peripheral Blood Leucocytes In Vitro
• Human Serum Ribonuclease Activity as a Marker for Therapeutic Success in Ovarian Carcinoma
• Biological Properties of the New Quinazoline Inhibitor of Thymidylate Synthetase CB 3717
• Miscellaneous
• Reactivation of Alkylation-Damaged Adenovirus 3 by Cell Cultures Derived from Human Tumours
• Effects of Surgical and Radio-Chemotherapeutic Treatment on the Immunological Pattern in Malignant Glioma Patients
• Control of Megacaryocyte Differentiation in Healthy and Leukemic Patients
• Cytotoxic T Lymphocytes: Various Effects on Human Myeloma Cells
• Analysis of AHH Inducibility Ratios and Distribution in Human Lymphocytes by TLC-Radioisotopic Assay
• Antitumour Actitivy of New Nitrosoureas on Yoshida Sarcoma Ascites Cells In Vivo
• The Mode of Action of Cyclophosphamide
• Index
• Appendix