Structure, functional aspects, metabolism

May 12–14, 1982, Leiden, The Netherlands

F. Haverkate

• Verlag: De Gruyter
• Jahr: 2019
• ISBN drucken:
  9783110089868
• eBook-ISBN:
  9783110850642
• Thema: Medizin
• Thema: Medizinische Theorie, Praxis & Referenz

Keine ausführliche Beschreibung für "Structure, functional aspects, metabolism" verfügbar.

Inhaltsverzeichnis

• Preface
• Contributors And Addresses
• Contents
• I. Physicochemical Aspects
• Hydrodynamic characterization of human fibrinogen
• Early plasmin digestion of fibrinogen: light scattering data
• Correlation of fibrinopeptide A release and light scattering during fibrinogen to fibrin transformation
• A kinetic approach to the polymerization of fibrin at high ionic strength
• Secondary Structure Of Fibrin
• II. Fibrinogen-Fibrin Conversion
• Synthetic peptide Gly-His-Arg-Pro activates fibrin monomers
• Fibrinopeptide characterization and kinetics of release in animal fibrinogens as analysed by highperformance liquid chromatography
• III. Interaction with Divalent Cations
• The topography of fibrinogen fragment D
• Calcium binding to fibrinogen investigated by rate of dialysis
• Calcium-binding sites and anticlotting properties of human fibrinogen and fibrin(ogen) fragments
• Binding of fibrinogen and degradation products to chelated zinc
• IV. Abnormal Fibrinogens
• Genetically abnormal fibrinogens - some current characterisation strategies
• Two-dimensional electrophoretic characterization (iso-dalt) of fibrinogen and fibrin subunit chains from four different genetic dysfibrinogen variants
• The molecular abnormality of fibrinogen Manchester
• Functional characterisation and protein chemical analysis of two new cases of dysfibrinogenemia, London III & IV
• Genetically abnormal fibrinogens releasing abnormal fibrinopeptides as characterised by high-performance liquid chromatography
• Sialic acid and sialyltransferase in the pathogenesis of acquired dysfibrinogenaemia
• V. Fibrinogen Derived Products in vitro and in vivo
• Comparative studies on F-CB3 related antigen, fibrinogen degradation products, soluble fibrin monomer complexes and fibrinogen in patients with renal carcinoma
• Characterization of crosslinked high molecular weight fibrin derivatives from in vitro and in vivo (ascitic fluid) material
• Immunochemical differentiation of fibrinogen, fragment D or E, and cross-linked fibrin degradation products using monoclonal antibodies
• Purification and properties of early (X-like) and late (D-like) fibrinogen fragments, produced by leukocyte elastase
• Formation of fibrin degradation products from a non-anticoagulated whole blood clot
• VI. Biosynthesis and Clearance
• Changes of synthesis of fibrinogen polypeptide and albumin mRNAs in rat liver after turpentine injection and after partial hepatectomy or laparotomy
• Role of kidney in eliminating low molecular weight fibrinogen derivatives from the circulation
• Clearance of I¹²⁵ fibrinogen and I¹³¹soluble fibrin in normals and in fibrinaemic patients: a pilot study
• Clearance of homologous fibrin monomers and fibrin(ogen) degradation products in the rat
• VII. Other Physiological Aspects of Fibrinogen
• Evidence for Specific sites in fibrin(ogen) that stimulate tissue activator catalyzed plasminogen activation
• Vasoactive Peptides Released From The ßß-Chain On Degradation Of Human Fibrin(Ogen) By Plasmin Or Elastase
• Interactions between fibrin and fibronectin. No effect of fibronectin on the plasma solubility of fibrin monomers
• Interactions between fibronectin and soluble fibrin - no effect of fibrin monomers upon the formation of the heparin precipitable fraction of plasma
• Author Index
• Subject Index