Sensitive Skin Syndrome

Golara Honari, Rosa Andersen, Howard L. Maibach, Golara Honari, Rosa Andersen, Howard L. Maibach

• Editorial: CRC Press
• Año: 2017
• ISBN:
  9781351647366
• Edición: 2
• Categoría: Medicine
• Categoría: Medical Theory, Practice & Reference

Sensitive skin is a widely reported condition where there is subjective cutaneous hyper-reactivity to environmental factors. Progress has been made in many aspects of the background science that will help clinicians in their management of patients presenting with the condition. This new text sums up the advances in thinking on pathophysiology, classification, methods of investigation, and the different susceptibilities of different types of skin.

Index

Page numbers followed by f and t indicate figures and tables, respectively.

A

A-α axons, 25

A-β fibers, 25, 32, 41, 100

Abnormal muscle contraction/relaxation, 46, 48

enhanced acidity and, 48

ACD, see Allergic contact dermatitis (ACD)

Acetyl-β-methylcholine chloride (vasodilators), 5, 7

Acetylcholine, 42

Acidity, enhanced, abnormal muscle contraction and, 48

Acid-sensing ion channels (ASICs), 30, 44, 198

Actin-bound myosin cross bridges, 49f

Acute dermal irritation/corrosion testing, 178–179, 178t

Acute irritants, 175

Acute irritations

vs. cumulative irritations, 91–92, 92f

AD, see Atopic dermatitis (AD)

Adenosine monophosphate-activated protein kinase, 49

A-δ fibers, 25, 27, 28, 32, 41, 42, 44

Adiponectin, 49–50, 50f, 198

ADIPOQ, 49–50, 50f, 198

Aerobic ATP synthesis, impaired, 46, 48

Afferents, 23; see also specific types

characteristics, 25t

African Americans, 39, 105, 106, 123, 127, 130

Age-related differences

potential causes, 111

self-reported sensitive skin, 109–111, 110t

sensitization responses, 108

sensory perception, 108

skin irritation responses, 108

Air pollutants, 150–151, 151t

indoor/outdoor, 150–151, 151t

persistent organic (POPs), 150

Air pollution

barrier function and, 152

defined, 150

inflammatory reactions, 152

overview, 150

oxidative stress, 151–152

skin and, 151–152, 153t–154t

Alcohol-based formulations, 196

Allergens, 5, 168, 196

Allergen-specific T cells, 169

Allergic contact dermatitis (ACD), 141–142, 145–146, 160

assessment, 169

causes, 141–142, 145–146, 160

effector phase, 169

induction phase, 168–169

in vitro t...